A volume overload refers generally to an expansion of the ECF volume. An expansion of the ECF volume typically occurs during heart failure, nephrotic syndrome and in liver cirrhosis. A renal sodium retention leads to an increase of total body sodium content. This increase results in varying degrees of volume overload. In heart failure, the decreased ECF volume leads to an increased effective circulating volume, which in turn causes the organ perfusion is reduced and brings clinical consequences. The serum sodium concentration with volume overload high, low or normal in patients to be (despite the increased whole body sodium content).

The increase in total body amount of sodium comes to the pathophysiological lead role. This increases the osmolality, which in turn triggers compensatory mechanisms that cause water retention. When sufficient fluid in the ECF collects (usually> 2.5 L), develop edema (edema).

A volume overload refers generally to an expansion of the ECF volume. An expansion of the ECF volume typically occurs during heart failure, nephrotic syndrome and in liver cirrhosis. A renal sodium retention leads to an increase of total body sodium content. This increase results in varying degrees of volume overload. In heart failure, the decreased ECF volume leads to an increased effective circulating volume, which in turn causes the organ perfusion is reduced and brings clinical consequences. The serum sodium concentration with volume overload high, low or normal in patients to be (despite the increased whole body sodium content). The increase in total body amount of sodium comes to the pathophysiological lead role. This increases the osmolality, which in turn triggers compensatory mechanisms that cause water retention. When sufficient fluid in the ECF collects (usually> 2.5 L), develop edema (edema). Among the most common causes of ECF volume overload include the following: heart failure cirrhosis nephrotic syndrome renal insufficiency premenstrual edema pregnancy Clinical indications are weight gain and edema. The diagnosis is made clinically. The treatment aims to correct the cause. The sodium dietary intake is limited. Diuretics are given in heart failure, liver cirrhosis, renal failure, and nephrotic syndrome. The location and the size of the edema depend on many factors, including whether the patient sat recently located or standing. Daily weight checks are the best way to control the progress of the therapy of ECF volume overload. The rate of correction of a ECF volume overload should be limited to 0.25-0.5 kg body weight / day, depending on the degree of volume overload (faster over a substantial excess, more slowly at a lower excess) and the other medical problems of the patient (slower with hypotension and renal insufficiency).

Health Life Media Team

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