The inhalation of industrial solvents and aerosol sprays can cause a state of intoxication. A long-term use can cause neuropathy and hepatotoxicity.

The use of volatile solvents (eg. Acetates, alcohol, chloroform, ether, aliphatic and aromatic hydrocarbons, chlorinated hydrocarbons, ketones) is further a problem that is endemic in adolescents. Ordinary products (. Eg glues and adhesives, paints, paint strippers, cleaning agents) containing these substances; thus the access for children and young people is easy. About 10% of teenagers in the US have ever inhaled volatile solvents. Typically, a cloth impregnated with solvent in a bag or container is kept at the mouth and nose; naturally volatilized vapors are then inhaled (puffing, rhinitis).

The inhalation of industrial solvents and aerosol sprays can cause a state of intoxication. A long-term use can cause neuropathy and hepatotoxicity. The use of volatile solvents (eg. Acetates, alcohol, chloroform, ether, aliphatic and aromatic hydrocarbons, chlorinated hydrocarbons, ketones) is further a problem that is endemic in adolescents. Ordinary products (. Eg glues and adhesives, paints, paint strippers, cleaning agents) containing these substances; thus the access for children and young people is easy. About 10% of teenagers in the US have ever inhaled volatile solvents. Typically, a cloth impregnated with solvent in a bag or container is kept at the mouth and nose; naturally volatilized vapors are then inhaled (puffing, rhinitis). Volatile solvents lead to a stimulation of the central nervous system, then there is a central nervous system depression. With frequent use, a partial tolerance and psychological dependence developed, but does not occur on withdrawal syndrome. Symptoms and signs Acute effects Acute symptoms such as dizziness, drowsiness, slurred speech and unstable gait occur early. Also impulsivity, agitation and irritability may occur. With increasing effect on the CNS to illusionary misjudgments, hallucinations and delusions develop. The user experiences a euphoric, dreamlike state ( “High”), culminating in a brief sleep. It is a delirium with confusion, psychomotor retardation, emotional lability, and thought disorder develops. The Intoxikationszustand may last only minutes, but longer than one hour. Sudden death can occur from respiratory failure or Atemwegsokklusion by CNS depression or heart rhythm disorders ( “sudden sniffiing death”, perhaps by a myocardial sensitization). Methylene chloride (dichloromethane) metabolized to carbon monoxide and inhalation of the product can cause a delayed onset of symptoms of carbon monoxide poisoning; the symptoms can persist for a longer period. Inhalation of methanol may cause a metabolic acidosis and retinal damage f├╝hren.Chronische effects Chronic inhalation of volatile hydrocarbons, the skin around the mouth and nose (Huffer eczema) irritate. Complications of long-term use due to the effect of the solvent or other toxic components (e.g., as lead in gasoline). Carbon tetrachloride can cause severe liver damage and kidney failure. Toluene can lead to degeneration of the white matter, renal tubular acidosis and hypokalemia. Damage to the brain, liver, pripheren nerves, kidneys and bone marrow can be caused by massive inhalation or special sensitivity. Abuse of inhalants during pregnancy can cause “solvent syndrome fetal” preterm birth and whose characteristics are similar to those of the fetal alcohol syndrome. Diagnosis Clinical Investigation Volatile solvents are not detected in routine drug screenings. Many of them and their metabolites can be detected by gas chromatography in specialized laboratories, but such an examination is rarely necessary or appropriate, except for forensic purposes. Treatment Supportive care Treatment of acute nicotine poisoning supportive. Use of catecholamines (z. B. in hypotension) should be avoided because of possible solvent-induced myocardial sensitization. The treatment of arrhythmias is a challenge, and there is no specific treatment guideline. Beta blockers may have some benefit. The therapy-dependent young people is difficult and relapses are common. Mostly, however, the use of solvents with late adolescence ends. Efforts should be made to improve the social skills of the patient and his status in the family, school and society at large. Symptoms and treatment of poisoning with certain solvents see Table: Symptoms and treatment of specific toxins.

Health Life Media Team

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