The vaginal carcinoma is usually a squamous cell carcinoma, which usually> 60 years in women. The most common symptom is an abnormal vaginal bleeding. The diagnosis is made by biopsy. The treatment for many small local carcinoma consists of hysterectomy with lymphadenectomy and Vaginektomie; for most other tumors, radiotherapy is performed.

Vaginalkarzinome are responsible for 1% of gynecologic malignancies in the United States. The average age at diagnosis is between 60 and 65 years. Risk factors include infection with the human papilloma virus and cervical or vulvar cancer. Intrauterine diethylstilbestrol exposure predisposed to clear cell adenocarcinoma of the vagina, this is rare, the median age at diagnosis is 19 years.

The vaginal carcinoma is usually a squamous cell carcinoma, which usually> 60 years in women. The most common symptom is an abnormal vaginal bleeding. The diagnosis is made by biopsy. The treatment for many small local carcinoma consists of hysterectomy with lymphadenectomy and Vaginektomie; for most other tumors, radiotherapy is performed. Vaginalkarzinome are responsible for 1% of gynecologic malignancies in the United States. The average age at diagnosis is between 60 and 65 years. Risk factors include infection with the human papilloma virus and cervical or vulvar cancer. Intrauterine diethylstilbestrol exposure predisposed to clear cell adenocarcinoma of the vagina, this is rare, the median age at diagnosis is 19 years. Most (95%) of the primary vaginal cancers are squamous; others are primary and secondary adenocarcinomas, squamous secondary (in older women), clear cell adenocarcinomas (in young women) and melanoma. The most common vaginal sarcoma botryoides, the sarcoma (embryonal rhabdomyosarcoma); it has the highest incidence around the age of 3. Most vaginal cancers occur in the upper third of the posterior vaginal wall. Their propagation takes place through continuous growth (in the local paravaginal tissues, urinary bladder or rectum), over the inguinal lymph nodes for lesions of the lower vagina, over pelvic lymph node lesions in the upper vagina or hematogenous. Symptoms and signs Most patients present with abnormal vaginal bleeding: postmenopausal, postcoital or bleeding between periods. Some also complain of aqueous Vaginalfluor or dyspareunia. A few patients are asymptomatic, and the lesion is found during a routine gynecological examination or investigation of an abnormal Pap tests. Vesicovaginal or rectovaginal fistula are complications of advanced disease. Diagnostic biopsy Clinical Staging A punch biopsy is usually diagnostic, but occasionally a wide local excision is necessary. The staging of tumors occurs clinically (see table: vaginal carcinoma on the stage) and is mainly based on physical examination, endoscopy, chest x-ray (detection of pulmonary metastases), and usually CT (detection of abdominal or pelvic metastases) (eg, cystoscopy, Proctoscopy.). Survival rates depend on the stage. Vaginal carcinoma after stage Stage Description 5-year survival rates * I Limited to the vaginal II 65-70% infection of the tissue subvaginal 47% III expansion up to the pool wall 30% IV Tumor spread through the pelvis out, or infection of the urinary bladder or rectal mucosa 15-20% * The prognosis is worse if the primary tumor is large or poorly differentiated. Treatment hysterectomy with lymphadenectomy Vaginektomie and in tumors that are confined to the upper wall of the vagina third of radiotherapy in most other tumors tumors in stage I within the upper Vaginaldrittels can with radical hysterectomy, upper Vaginektomie and pelvic lymph node dissection can be treated. Most other primary tumors are treated with radiation therapy, usually a combination of radiotherapy and brachytherapy. Is a radiation therapy contraindicated due vesikovaginaler or rectovaginal fistula, a pelvic exenteration is performed.

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