(Microangiopathic haemolytic anemia)
The traumatic hemolytic anemia is an intravascular hemolysis that occurs due to excessive shearing forces or turbulence in the blood circulation.
Trauma can occur
The traumatic hemolytic anemia is an intravascular hemolysis that occurs due to excessive shearing forces or turbulence in the blood circulation. Trauma can occur outside of the vessel, as in the case of an impact on the skeleton such. B. due to repeated kicks (Marsch-hemoglobinuria), a Karate shock or hand drumming Within the heart, along a pressure gradient, as in calcified aortic stenosis, or due to a defective aortic valve In arterioles, as in severe (especially malignant) hypertension, some malignant tumors, or polyarteritis nodosa In Endarteriolen, often fibrin, as in thrombotic thrombocytopenic purpura and disseminated intravascular coagulation the damage leads to unusually shaped erythrocytes fragments (eg. as triangles, helmet forms), referred to in the peripheral blood as schistocytes. Their appearance in the peripheral blood smear is diagnostic cause the small schistocytes a low mean corpuscular volume and a high red blood cell distribution width (the latter reflects the Anisozytose resist). Treatment depends on the underlying process. Iron deficiency anemia due to chronic hemosiderinuria sometimes superimposed on the hemolysis. Is iron deficiency anemia is present, this is responsive to iron replacement therapy.