The toxic shock syndrome (TTS) is caused by staphylococcus or streptococcal exotoxins. The symptoms consist of high fever, hypotension, diffuse erythematous rash and multiple organ failure, which can move rapidly into serious and difficult to treat shock. The diagnosis is made clinically and by cultural detection of pathogens. The therapy includes antibiotics, intensive care and immunoglobulins.
TSS is caused by exotoxin-producing cocci. Staphylococcus aureus strains of the phage group 1 set the TSS toxin free 1 (TSST-1) or related exotoxins, certain Streptococcus pyogenes strains produce at least 2 exotoxins.
The toxic shock syndrome (TTS) is caused by staphylococcus or streptococcal exotoxins. The symptoms consist of high fever, hypotension, diffuse erythematous rash and multiple organ failure, which can move rapidly into serious and difficult to treat shock. The diagnosis is made clinically and by cultural detection of pathogens. The therapy includes antibiotics, intensive care and immunoglobulins. TSS is caused by exotoxin-producing cocci. Staphylococcus aureus strains of the phage group 1 set the TSS toxin free 1 (TSST-1) or related exotoxins, certain Streptococcus pyogenes strains produce at least 2 exotoxins. Toxic shock caused by staphylococci have the highest risk for staphylococcal TSS women with a pre-existing staphylococcal colonization of the vagina and the tampon or other aids in the vagina can (z. B. contraceptive sponges, diaphragms). The use of these tampons increasingly likely due to mechanical or chemical factors, the production of exotoxin or facilitate its transfer into the bloodstream through a Mucosaschrankenstörung or the uterus. On small numbers of cases based estimates suggest that continue to occur about 3 cases of 100,000 menstruating women still are cases observed in women using tampons and women who have an infection after childbirth or abortion. About 15% of cases occur as postpartum or as a complication of postoperative staphylococcal wound infections, which often appear inconspicuous. also cases in men and women with any type of S. aureus infection were reported. The lethality of staphylococcal TSS is <3%. Relapses can occur particularly often in women who continue to use tampons during the first four months after the disease. LLLToxischer shock streptococcal The syndrome is similar to that caused by S. aureus, but mortality is despite aggressive therapy higher (20-60%). In addition, it comes with about 50% of the cases to a S. pyogenes bacteremia, and 50% of patients have einenekrotisierende fasciitis (both come in staphylococcal TSS not heaped in front). There are usually otherwise healthy children or adults are affected. Primary infections of the skin and soft tissues are more common than in other places. In contrast to staphylococcal -TSS a streptococcal TSS leads are more likely to lead to acute respiratory distress syndrome (ARDS) and less frequently to typical skin reactions. S. pyogenes TSS is defined as any infection with ?-hemolytic group A streptococci (GABHS) associated with shock and organ failure. Risk factors for GABHS TSS are Minor Trauma Surgical Procedures viral infections (eg. As chickenpox) The use of NSAIDs symptoms and complaints The disease begins suddenly with fever (39 ° -40.5 ° C, persistent), hypotension (which may be refractory can), a diffuse macular erythema and participation of at least two other organ systems. A staph TSS] is often accompanied by vomiting, diarrhea, myalgia, elevated CK, mucositis, liver cell damage, thrombocytopenia and confusion. Staphylococcal TSS rash often leads to flaking of the skin, especially the palms and soles, between the 3rd and 7th day after starting. The streptococcal TSS often goes with ARDS (about 55% of patients), coagulopathy and liver damage associated and often results in fever, malaise, and severe pain at the site of soft tissue infection. Kidney involvement occurs frequently in both forms. The syndrome can lead within 48 h to syncope, shock and death. Less severe cases of staphylococcal TSS are relatively common. Staphylococcal toxic shock syndrome Image courtesy of the Public Health Image Library of the Centers for Disease Control and Prevention. var model = {thumbnailUrl: '/-/media/manual/professional/images/staphylococcal_scalded_skin_c_orig_high_de.jpg?la=de&thn=0&mw=350' imageUrl: '/-/media/manual/professional/images/staphylococcal_scalded_skin_c_orig_high_de.jpg?la = en & thn = 0 ', title:' staphylococcal toxic shock syndrome ', description:' u003Ca id = "v38396468 " class = ""anchor "" u003e u003c / a u003e u003cdiv class = ""para "" u003e u003cp u003eDas toxic shock syndrome caused by staphylococcus a diffuse erythematous rash. In the late course of the disease it comes to scaling