Nilutamide [not available in Germany]
Cyproterone acetate [not available in the US]). A combined androgen blockade typically refers to treatment with LHRH agonist plus anti-androgens
but their advantage over a sole LHRH agonist (or degarelix or orchiectomy) is slightly larger. (Because of leading to worsening of symptoms testosterone increase upon initiation of therapy recommended with an LHRH agonist. The guidelines of the German Society of Urology n. D. Übers .: u a.
to prescribe as a so-called “flare-up” prophylaxis before the first administration of the LHRH agonist limited in time (1-2 weeks) an antiandrogen.) Another possibility is an intermittent androgen blockade