Vancomycin is a time-dependent, bactericidal antibiotic that inhibits cell wall synthesis. Pharmacology Vancomycin is practically nichtresorbiert after oral administration of the normal GI tract. After parenteral administration, it penetrates into the bile and pleural, pericardial, synovial and ascites. However, the penetration into the inflamed CSF is small and irregular. Vancomycin is excreted unchanged by glomerular filtration. Indications Vancomycin is active against most Gram-positive cocci and rods, including virtually all Staphylococcus…

September 3, 2018