Tumor Antigens

Tumor-associated antigens (TAA) are mostly restricted to tumor cells, whereas tumor-specific antigens (TSA) occur exclusively on tumor cells. TSA and TAA are typically parts of intracellular molecules (MHC) are presented on the cell surface as part of the major histocompatibility complex. Many tumor cells produce antigens that are released either into the bloodstream or remain on the cell surface. Antigens were found in most human tumors (eg. As Burkitt’s lymphoma,…

September 3, 2018