Tropical Spastic Paraparesis / Htlv-1 Associated Myelopathy (Tsp / Ham)

The tropical spastic paraparesis / HTLV-1 associated myelopathy (TSP / HAM) is a slowly progressive, viral, immune-mediated disease of the spinal cord and is caused by the human T-lymphotropic virus 1 (HTLV-1). It causes spastic paralysis of both legs. The diagnosis is made by serological tests and PCR of serum and cerebrospinal fluid. Treatment includes supportive care and possibly immunosuppressive therapies. (See also overview of diseases of the spinal cord.)…

September 3, 2018