Effects Of Liver Disease On The Drug Metabolism

The clinical effects may v. a. vary in chronic liver diseases regardless of the bioavailability of the drugs, for. B. increased cerebral sensitivity to opiates and sedatives in patients with common chronic liver diseases. Therefore, low doses of these drugs appears to cause encephalopathy, when administered cirrhotic patients. The underlying mechanism for this effect is likely due to changes in the cerebral receptors for the appropriate medication. A liver disease…

September 3, 2018
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