Autoimmune Metaplastic Atrophic Gastritis

An autoimmune metaplastic atrophic gastritis (AMAG) is an inherited autoimmune disease that affects the parietal cells and leads to hypochlorhydria and decreased production of intrinsic factor. Following are atrophic gastritis, a vitamin B12 malabsorption and often pernicious anemia. The risk of a gastric adenocarcinoma is increased by 3 times. The diagnosis is made endoscopically. The treatment consists of parenteral administration of vitamin B12. Patients with AMAG have antibodies against parietal…

September 3, 2018