Syphilis is caused by the spirochete Treponema pallidum and is characterized by 3 consecutive clinical, symptomatic stages, which are divided by periods of asymptomatic latent infections. Common manifestations include genital ulcers, skin lesions, meningitis, Aortic and neurological syndromes. The diagnosis is made by serological testing and additional studies that are based on the stage of the disease. Penicillin is the drug of choice.

Syphilis is caused by the spirochete Treponema pallidum and is characterized by 3 consecutive clinical, symptomatic stages, which are divided by periods of asymptomatic latent infections. Common manifestations include genital ulcers, skin lesions, meningitis, Aortic and neurological syndromes. The diagnosis is made by serological testing and additional studies that are based on the stage of the disease. Penicillin is the drug of choice.

(Congenital syphilis.) Syphilis is caused by the spirochete Treponema pallidum and is characterized by 3 consecutive clinical, symptomatic stages, the asymptomatic periods by latent infection are divided. Common manifestations include genital ulcers, skin lesions, meningitis, Aortic and neurological syndromes. The diagnosis is made by serological testing and additional studies that are based on the stage of the disease. Penicillin is the drug of choice. Syphilis is caused by T. pallidum, a spirochete that can not survive for long outside the human body. T. pallidum penetrates through mucous membranes or skin into the body, reached the regional lymph nodes within hours and is rapidly spreading all over the body. A syphilis disease occurs in a primary, secondary, and tertiary stage (see Table: Classification of syphilis), with long latency periods in between. Infected people are contagious during the first two stages. Classification of syphilis Stage Description symptoms and complaints Acquired primary contagious chancre (a small, usually painless skin wound), regional lymphadenopathy secondary Contagious kick weeks to months after the first stage of rash (which can be confused with those of various other diseases) inflammation of the mucous membranes, hair loss , Fever, many other symptoms latent asymptomatic; Can not continue contagious indefinitely or be followed by late stage disease Early latent syphilis (infection <1 year duration), sometimes late with recurrent infectious lesions latent syphilis (infection ? 1 year duration), rarely with recurrence; positive serological tests late or tertiary Symptomatic; not contagious clinically as benign tertiary syphilis, cardiovascular syphilis or neurosyphilis (. eg asymptomatic, meningo-vascular or parenchymal neurosyphilis, tabes dorsalis) classified Congenital * Early symptoms: Symptomatic appearance to obvious to the age of 2 years disease Late symptoms Symptomatic kick later in life on Hutchinson's teeth, eye or bone abnormalities * Can also exist in a permanent latent (asymptomatic) stage. The infection is usually transmitted through sexual contact (including genital, orogenital and anogenital), but can also not be sexually transmitted by skin contact or transplacental be (congenital syphilis). The risk of transmission is for a single sexual contact with a person with a primary syphilis approximately 30% and 60-80% for an infected mother to the fetus. A previous infection does not lead to immunity to reinfection. Symptoms and complaints Syphilis can manifest itself at any stage, involve multiple or individual organs and mimic many other disorders. The course of syphilis can be accelerated by a concurrent HIV infection; In these cases, eye involvement, meningitis and other neurological complications are more frequent and more severe. Syphilis primary (genital chancre) Image courtesy of Drs. Gavin Hart and N. J. Flumara on Public Health Image Library of the Centers for Disease Control and Prevention. var model = {thumbnailUrl: '/-/media/manual/professional/images/syphilis_primary_genital_orig_high_de.jpg?la=de&thn=0&mw=350' imageUrl: '/-/media/manual/professional/images/syphilis_primary_genital_orig_high_de.jpg?la = en & thn = 0 ', title:' syphilis primary (genital chancre) 'description:' u003Ca id = "v37896210 " class = ""anchor "" u003e u003c / a u003e u003cdiv class = ""para "" u003e u003cp u003eSyphilitische chancre may appear on or around the genitals u003c / p u003e u003c / div u003e 'credits'. image courtesy of Drs Gavin Hart and NJ Flumara over. Public Health Image Library of the Centers for Disease Control and Prevention '

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