(Vitamin B2)
A riboflavin deficiency usually occurs with other B vitamin deficiencies. Symptomatic are a sore throat, lesions of the lips and oral mucosa, glossitis, conjunctivitis, seborrheic dermatitis and normochromic, normocytic anemia. The diagnosis is made clinically in general. To treat riboflavin is i.m. orally or as needed administered.
Riboflavin acts as an essential coenzyme in carbohydrate metabolism in numerous redox reactions with (see table: sources, functions and effects of vitamins). Riboflavin is not toxic.
(See also overview of vitamins.) Riboflavin acts as an essential coenzyme in carbohydrate metabolism in numerous redox reactions with (see table: sources, functions and effects of vitamins). Riboflavin is not toxic. A riboflavin riboflavin deficiency usually occurs with other B vitamin deficiencies. Symptomatic are a sore throat, lesions of the lips and oral mucosa, glossitis, conjunctivitis, seborrheic dermatitis and normochromic, normocytic anemia. The diagnosis is made clinically in general. To treat riboflavin is i.m. orally or as needed administered. Etiology A primary riboflavin deficiency caused by the inadequate supply of the following products: cereals enriched milk Other animal products A secondary riboflavin deficiency is most commonly caused by: Chronic diarrhea malabsorption syndromes liver damage hemodialysis peritoneal dialysis Long-term use of barbiturates chronic alcoholism symptoms and complaints The usual symptoms of riboflavin deficiency are paleness and maceration of the mucosa in the mouth (stomatitis angularis) and vermillion-colored lips (cheilosis) on which eventually form superficial linear fissures. These infected optionally substituted with Candida albicans, consequently grayish white lesions arise (Perlèche). The tongue turns deep red. In the nasolabial folds, ears, eyelids, on the scrotum or the labia majora, a seborrheic dermatitis develops. These skin areas become red, scaly and greasy. In rare cases, it leads to neovascularization and keratits the cornea followed by watery eyes and Photophobie.Diagnose therapeutic trial Riboflavinausscheidung in urine The characteristic of a riboflavin deficiency lesions have no specific characteristics. A riboflavin deficiency is considered when the characteristic symptoms, patients with other B vitamin deficiencies. The diagnosis of riboflavin deficiency can be in a therapeutic trial or confirmed by laboratory tests in which measured in the urine of the Riboflavinausscheidung wird.Therapie oral riboflavin and other water-soluble vitamins riboflavin is given orally once daily at a dose of 5-10 mg until recovery. The patient should also more water-soluble vitamins erhalten.Wichtige points A riboflavin deficiency causes various non-specific skin and mucous membrane lesions, including maceration of the mucosa of the mouth (angular stomatitis) and surfaces of the lips (cheilosis). Go from a riboflavin deficiency in patients with characteristic symptoms and other vitamin B deficiencies; confirm this suspicion with a therapeutic trial with dietary supplements or the measurement of urinary excretion of riboflavin. Treatment with intake of riboflavin and other water-soluble vitamins.