The airways may be affected by primary tracheobronchial tumors, primary tumors that are located next to the respiratory tract and invade them or compress them, or cancer that metastasized to the airways.

Primary tumors of the trachea are rare (0.1 / 100,000). They are often malignant and are detected in locally advanced stages. The most common malignant Trachealtumoren are adenoid cystic carcinoma, squamous cell carcinoma, carcinoid tumors and Mukoepidermoidkarzinome. The most common benign tumors are respiratory papillomas, although pleomorphic adenomas and granular cell and benign cartilaginous tumors also occur.

The airways may be affected by primary tracheobronchial tumors, primary tumors that are located next to the respiratory tract and invade them or compress them, or cancer that metastasized to the airways. Primary tumors of the trachea are rare (0.1 / 100,000). They are often malignant and are detected in locally advanced stages. The most common malignant Trachealtumoren are adenoid cystic carcinoma, squamous cell carcinoma, carcinoid tumors and Mukoepidermoidkarzinome. The most common benign tumors are respiratory papillomas, although pleomorphic adenomas and granular cell and benign cartilaginous tumors also occur. Symptoms and complaints The patients often exhibit dyspnea coughing wheezing stridor hemoptysis hemoptysis may occur in squamous and possibly lead to earlier diagnoses, while wheezing and stridor occur more frequently in adenoid cystic carcinoma. Dysphagia and hoarseness may also occur and are mostly initial indication of a more advanced disease. Diagnostic biopsy Bronchoscopic Symptoms of Atemwegverengung (z. B. wheezing, shortness of breath, difficulty breathing) announce a life-threatening airway obstruction. A Atemwegtumor should be considered as a possible cause, if such symptoms are inexplicable, with other symptoms of Atemwegtumoren (z. B. unexplained hemoptysis) are of insidious onset, are associated and poorly on standard treatments respond (z. B. when asthma treatments wheezing do not improve). When a Atemwegtumor is suspected, the patient will need an immediate evaluation with bronchoscopy. Bronchoscopy allows both the treatment of airflow obstruction and obtaining samples for diagnosis. Is a cancer found, carried out extensive tests for staging. Prognosis The prognosis depends on the histology. Squamous tend to metastasize to regional lymph nodes and infiltrate mediastinal structures directly, which results in high local recurrence rate and relapse rates in the neighborhood. Even with definitive surgical resection, the 5-year survival rate is only 20-40%. Adenoid cystic carcinomas are typically not painful, but tend to metastasize to the lungs and perineural, resulting after resection to high recurrence rates. Nevertheless, these patients due to the lower growth rate of 60-75% higher 5-year survival rate. Treatment Surgical procedures Sometimes radiotherapy methods for obstruction reduction Primary respiratory tumors should, if possible, be treated definitively with surgical resection. Resections of the trachea, larynx and trachea or Carina are the most common operations. Up to 50% of Tracheallänge can be safely removed with a primary end-to-end anastomosis. If a lung or thyroid cancer infiltrates the trachea, surgery is sometimes still possible if the studies suggest sufficient tissue to reconstruct the trachea. Can not be free of tumor operated on the margins, adjuvant radiotherapy is recommended. Most primary Trachealtumoren are inoperable due to metastasis, locally advanced stages or accompanying diseases of the patient. In the case of endoluminal tumors, the tumor with a therapeutic bronchoscopy can be centrally hollowed out. Other techniques for removing obstruction include laser vaporization, photodynamic therapy, cryotherapy, and brachytherapy endobronchial. Tumors that compress the trachea are treated with stenting, radiotherapy or both. Summary Primary tracheal tumors are rare, often malignant and usually locally advanced, if they are detected. Atemwegtumore be suspected in patients with progressive, unexplained or untreatable dyspnea, coughing, wheezing, hemoptysis, and stridor. The treatment is carried out with local resection, or if resection is not indicated, with other locally destructive therapies.

Health Life Media Team

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