It is an episodic inflammatory disease with destruierendem character, v. a. can affect the cartilage of the ear and nose, but occasionally the eyes, the tracheobronchial tree, the heart valves, kidneys, joints, skin and blood vessels. The diagnosis is made by a combination of clinical, laboratory, imaging and occasionally biopsy findings. The treatment is usually of corticosteroids and immunosuppressive drugs given.
Women and men are equally affected by the polychondritis, it occurs most frequently in middle age. Associations with RA, SLE, systemic vasculitis and other connective tissue diseases suggest an autoimmune etiology.
It is an episodic inflammatory disease with destruierendem character, v. a. can affect the cartilage of the ear and nose, but occasionally the eyes, the tracheobronchial tree, the heart valves, kidneys, joints, skin and blood vessels. The diagnosis is made by a combination of clinical, laboratory, imaging and occasionally biopsy findings. The treatment is usually of corticosteroids and immunosuppressive drugs given. Women and men are equally affected by the polychondritis, it occurs most frequently in middle age. Associations with RA, SLE, systemic vasculitis and other connective tissue diseases suggest an autoimmune etiology. Symptoms and signs Acute pain, erythema and swelling affecting the ear most often. The second most frequent is an inflammation of the nasal cartilage, followed by arthritis, which may vary from arthralgia to symmetrical or asymmetrical nichtdestruierenden arthritis of the large and small joints, preferably infest are the costochondral joints and knees. Other frequent manifestations are – with decreasing frequency – eye inflammation (. Eg conjunctivitis, scleritis, iritis, keratitis, chorioretinitis), cartilage portions of the larynx, trachea and bronchial tree (with hoarseness, cough and pain over the laryngeal cartilage), inner ear, cardiovascular system (z. B. regurgitations of the aortic valve, peri- and myocarditis, aortic aneurysms, aortitis), kidney and skin. Acute inflammatory attacks sound over weeks to months off, relapses can occur for many years. Recurrent polychondritis (ear) © Springer Science + Business Media var model = {thumbnailUrl: ‘/-/media/manual/professional/images/397_relapsing_polychondritis_slide_4_springer_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / ? manual / professional / images / 397_relapsing_polychondritis_slide_4_springer_high_de.jpg lang = en & thn = 0 ‘, title:’ Recurrent polychondritis (ear) ‘description:’ u003Ca id = “v37892771 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDer cartilaginous part (pinna) of the ear is purple and swollen u003c / p u003e u003c / div u003e ‘credits’. © Springer Science + Business Media ‘