Psoriasis is an inflammatory disease, which usually goes hand in hand with sharply limited erythematous papules and plaques covered with silvery scales. Several factors, including genetics, contribute to it. Common triggers are injuries, infections and certain drugs. Symptoms are usually minimal, but it can occur more easily to severe itching. The cosmetic consequences can be great. Some patients develop severe disease with painful arthritis. The diagnosis is made based on the appearance and distribution of lesions. The treatment may comprise emollients, Vitamin D analogs, topical retinoids, tar, anthralin, corticosteroids, phototherapy and in severe cases, methotrexate, oral retinoids, immunomudolatorische agent (Bilogics) and immunosuppressants.

In psoriasis is hyperproliferation of epidermal keratinocytes with accompanying inflammation of the epidermis and dermis. It affects 1-5% of the world population. Fair-skinned people have a higher risk of disease, dark-skinned lower. There are roughly two peak incidence: Most people are diagnosed with 16-22 years or 57-60 years, but the disease can occur at any age.

Psoriasis is an inflammatory disease, which usually goes hand in hand with sharply limited erythematous papules and plaques covered with silvery scales. Several factors, including genetics, contribute to it. Common triggers are injuries, infections and certain drugs. Symptoms are usually minimal, but it can occur more easily to severe itching. The cosmetic consequences can be great. Some patients develop severe disease with painful arthritis. The diagnosis is made based on the appearance and distribution of lesions. The treatment may comprise emollients, Vitamin D analogs, topical retinoids, tar, anthralin, corticosteroids, phototherapy and in severe cases, methotrexate, oral retinoids, immunomudolatorische agent (Bilogics) and immunosuppressants. In psoriasis is hyperproliferation of epidermal keratinocytes with accompanying inflammation of the epidermis and dermis. It affects 1-5% of the world population. Fair-skinned people have a higher risk of disease, dark-skinned lower. There are roughly two peak incidence: Most people are diagnosed with 16-22 years or 57-60 years, but the disease can occur at any age. Etiology The cause is unclear, but includes immune stimulation of epidermal keratinocytes. T cells appear to play a central role. Family history is widespread and certain genes and HLA antigens (Cw6, B13, B17) are associated with psoriasis. The PSORS1 on chromosome 6p21 locus determined likely to develop psoriasis susceptibility of a patient. It is believed that the inflammatory response is triggered with subsequent hyperproliferation of keratinocytes of environmental factors. Specifically identified triggers include injury (Koebner phenomenon) sunburn HIV ?-hemolytic streptococcal infection drugs (especially ?-blockers, chloroquine, lithium, ACE inhibitors, indomethacin, terbinafine, and interferon-alfa) Emotional stress alcohol consumption tobacco use obesity symptoms and complaints lesions are either asymptomatic or itchy and often on the scalp, extensor surfaces of the elbows and knees, the sacrum, buttocks (usually the Analrinne) and the genitals found. Also nails, eyebrows, armpits, navel and the perianal area may be affected. With more extensive involvement, the lesions of these areas of skin with each other coalesce. Depending on the lesions differ in appearance from psoriasis form. Psoriasis (elbow) Science Photo Library var model = {thumbnailUrl: ‘/-/media/manual/professional/images/c0225511_psoriasis_of_the_elbows_science_photo_library_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / manual / professional / images / c0225511_psoriasis_of_the_elbows_science_photo_library_high_de.jpg lang = en & thn = 0 ‘, title:’? psoriasis (elbow) ‘description:’ u003Ca id = “v37894962 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDiese figure shows reddened patches covered with silvery white scales on the extensor side of the elbow u003c / p u003e u003c / div u003e. ‘credits’ Science Photo Library ‘

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