Proteusverwandte pathogens are members of the normal intestinal flora, which can often lead (by antibiotic therapy z. B.) infections in patients with impaired intestinal flora.

The proteusverwandten agents form at least three genera of gram-negative organisms:

Proteusverwandte pathogens are members of the normal intestinal flora, which can often lead (by antibiotic therapy z. B.) infections in patients with impaired intestinal flora. The proteusverwandten agents form at least three genera of gram-negative organisms: Proteus mirabilis, P. vulgaris and P. myxofaciens Morganella: M. morganii Providencia P. rettgeri, P. alcalifaciens, and P. stuartii Most infections, however, are of P . mirabilis caused. These pathogens belong to the physiological intestinal flora and are also present in soil and water. They often occur in superficial wounds in the ear canal and sputum, particularly in patients whose physiological flora has been eradicated by antibiotic therapy. They can cause bacteremia and deep infections, particularly in the ears, sinus cells of the mastoid, the peritoneal cavity and the urinary tract in patients with chronic urinary tract infections or kidney or bladder stones; Proteus-organisms produce urease Urea is hydrolyzed, resulting in the formation of alkaline urine and struvite stones (ammonium magnesium phosphate) leads. P. mirabilis is usually sensitive to ampicillin, carbenicillin, ticarcillin, piperacillin, cephalosporins, fluoroquinolones and aminoglycosides and tetracyclines resistant. Multidrug-resistant P. mirabilis is an emerging problem. Indolpositive species (P. vulgaris, M. morganii, P. rettgeri) tend to be more resistant, but usually still sensitive to fluoroquinolones, carbapenems, piperacillin / tazobactam, cephalosporins of the 3rd generation and cefixime.

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