The primary hepatocellular carcinoma is mostly a hepatocellular carcinoma (HCC). The first symptoms of liver cancer are usually nonspecific, which delays the diagnosis. The prognosis is usually poor. Other primary hepatocellular carcinomas other primary liver cancers are rare or very rare. The diagnosis requires a biopsy evaluation generally. The prognosis is typically poor. Some localized cancers can be resected. Resection or liver transplantation may prolong survival. Fibrolamellar carcinoma This special form of hepatocellular carcinoma has a characteristic morphology of malignant degenerate hepatocytes embedded in lamellar fibrous tissue. It occurs usually in young adults, has no association with preexisting cirrhosis, HBV or HCV or other known risk factors. The alpha-fetoprotein (AFP) levels are usually increased. The prognosis is better than in hepatocellular carcinoma, and many patients survive for several years after Tumorresektion.Gallengangskarzinom This tumor arises from cells of Gallengangsepithels. The cholangiocarcinoma is common in China, where it is assumed that the infection contributes to liver fluke disease. Otherwise, it is less common than hepatocellular carcinoma mixed forms occur. Primary sclerosing cholangitis Although rare increases the risk of bile duct carcinoma significantly (1) .Hepatoblastom, is the most common primary liver hepatoblastoma one of the cancers in infants, especially where a family history of adenomatous polyposis. They can form in children also. In some patients, the hepatoblastoma manifested as precocious puberty caused by ectopic gonadotropin. In general, the cancer is diagnosed, however, because of a deterioration in the general condition and the detection of a mass in the right upper abdomen. An elevated AFP levels and pathological findings in the imaging procedures are for diagnosis hilfreich.Angiosarkom This rare tumor with specific chemical carcinogens incl. Industrially produced vinyl chloride assoziiert.Zystadenokarzinome This rare disease is probably secondary to the malignant transformation of a cystadenoma before and is often multilobular. Treatment consists of resection. Note Razumilava N, Gores GJ, Lindor KD. Cancer surveillance in patients with primary sclerosing cholangitis. Hepatology 54 (5): 1842-1852., 2011

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