The compound used most frequently in clinical PET

Positron emission tomography (PET), a kind of radionuclide scintigraphy, substances used include radionuclides, which release when breaking up a positron (? +), the antimatter equivalent of an electron. The free positron combines with an electron and incurring two photons whose paths differ by 180 ° from each other. Around the positron emission source annular detector systems are arranged which detect both photons simultaneously and so locate the source and be able to produce colored tomographic images of the region. Since positron-emitting radionuclides are embedded in metabolically active substances, the PET can provide information on the function of tissues. The standard uptake value (SUV) indicates metabolic activity of a lesion; typically, the color intensity increases with higher SUVs. The compound most widely used in clinical PET fluorine-18 [18F] -labeled performed deoxyglucose. FDG is a glucose analog, whose recording is proportional to the glucose metabolism. The relative rate of metabolism of glucose, (SUV) is calculated by dividing the amount taken up by the injected dose and body weight of the patient. Use of PET PET is suitable for various clinical indications such. As cancer (eg. As staging and evaluation of certain types of cancer and evaluation of response to treatment), this indication has a share of about 80% of PET use cardiac function (eg. B. Evaluation of myocardial viability, detection of hibernating myocardium) Neurological function (z. B. evaluation of dementia and seizures) PET applications to be further investigated. Not all applications are refundable in the United States. Variants PET PET-CT imaging courtesy of Hakan Ilaslan, MD. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/fdg_pet_ct_reconstruction_histiocytosis_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/fdg_pet_ct_reconstruction_histiocytosis_high_de.jpg?la = en & thn = 0 ‘, title:’ PET PET-CT ‘, description:’ u003Ca id = “v37899002 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDas coronal reconstruction image of an FDG-PET-CT examination shows intense metabolic activity in the area of ??the left seat leg (arrows) according to the known histiocytosis of the patient. u003c / p u003e u003c / div u003e ‘ credits: ‘image courtesy of Hakan Ilaslan


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