P. jirovecii is a common cause of pneumonia in immunosuppressed patients (pneumonia in immunocompromised patients), especially in patients with HIV and those receiving systemic corticosteroids. The symptoms include fever, dyspnea and dry cough. For the diagnosis of pathogen detection of an induced sputum sample or Bronchoskopieprobe is required. Treatment is with antibiotics, usually trimethoprim / sulfamethoxazole or dapsone / trimethoprim, clindamycin / primaquine, atovaquone or pentamidine. Patients with PaO 2 <70 mmHg received systemic corticosteroids. The prognosis is good with timely treatment in general.

P. jirovecii is a ubiquitous microorganism is transmitted by droplet infection and disease in immunocompetent no triggers (overview of pneumonia (pneumonia)). However, some patients have to develop a P. jirovecii pneumonia risk:

P. jirovecii is a common cause of pneumonia in immunosuppressed patients (pneumonia in immunocompromised patients), especially in patients with HIV and those receiving systemic corticosteroids. The symptoms include fever, dyspnea and dry cough. For the diagnosis of pathogen detection of an induced sputum sample or Bronchoskopieprobe is required. Treatment is with antibiotics, usually trimethoprim / sulfamethoxazole or dapsone / trimethoprim, clindamycin / primaquine, atovaquone or pentamidine. Patients with PaO 2 <70 mmHg received systemic corticosteroids. The prognosis is good with timely treatment in general. P. jirovecii is a ubiquitous microorganism is transmitted by droplet infection and disease in immunocompetent no triggers (overview of pneumonia (pneumonia)). However, some patients have the risk of a P. jirovecii pneumonia to develop: Patients with HIV infection and CD4 + counts <200 / ul patients with organ transplant patients with hematologic cancers, patients taking corticosteroids, most patients suffer from fever, dyspnea and a dry, nonproductive cough that within a few weeks (HIV infection), or in a few days (other causes of restricted cellular immune defense) occurs. Dyspnea is common. Diagnostic chest X-ray pulse oximetry Histopathological confirmation Patients should be performed chest X-ray and assessment of oxygenation by pulse oximetry. In the chest X-ray to diffuse bilateral infiltrates perihilar typically; However, 20-30% of patients have an uneventful radiographic findings. Hypoxemia may exist even if the chest X-ray shows no infiltration; this finding may be an important clue to the diagnosis. If pulse oximetry is abnormal, often BGA be carried out to show the severity of hypoxemia (including an increase in the alveolar-arterial O2Gradienten). Tips and risks In immunosuppressed patients who have a dry, non-productive cough and abnormal chest x-ray or pulse oximetry, is done more testing for P. jirovecii pneumonia. If performed lung function tests show a limited diffusion capacity (although this is rarely performed as a diagnostic test). Clinical Calculator: A-a gradient Histopathologic demonstration of the organism to confirm the diagnosis is needed. Methenamine silver staining, Giemsa staining after Wright-Giemsa, modified Grocott staining, Weigert Gram staining or staining using monoclonal antibodies are used. sputum samples are typically obtained by induced sputum or bronchoscopy. The sensitivity ranges from 30-80% in induced sputum and> 95% for bronchoscopy with BAL-derived material. Pneumocystis pneumonia with permission of the publisher. From Huang L., P. Piliero In Bone’s Atlas of Pulmonary and Critical Care Medicine. Edited by J. Crapo. Philadelphia, Current Medicine, 2005. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/pneumocystis_pneumonia_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / manual / professional / images / pneumocystis_pneumonia_high_de.jpg lang = en & thn = 0 ‘, title:’? pneumocystis pneumonia ‘, description:’ u003Ca id = “v38395482 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eR√∂ntgenthorax an HIV-infected patients with u003ci u003ePneumocystis u003c / i u003eLungenentz√ľndung

Comments

Leave a Reply

Sign In

Register

Reset Password

Please enter your username or email address, you will receive a link to create a new password via email.