The success of a closed pleural biopsy is about two times higher in TB than in pleural cancers. Improved laboratory methods, newer diagnostic tests for pleural fluid (eg. As adenosine deaminasespiegel, interferon-gamma, PCR tests for suspected TB) and more widespread availability of thoracoscopy have made the process less necessary and it is therefore rarely performed.

A pleural is carried out to determine the cause of an exudative pleural effusion, thoracentesis when a is not diagnostically. The success of a closed pleural biopsy is about two times higher in TB than in pleural cancers. Improved laboratory methods, newer diagnostic tests for pleural fluid (eg. As adenosine deaminasespiegel, interferon-gamma, PCR tests for suspected TB) and more widespread availability of thoracoscopy have made the process less necessary and it is therefore rarely performed. Percutaneous pleural biopsy should be performed only by a lung specialist or surgeon who is trained in this procedure and only in patients who are cooperative and have no coagulation disorders. The technique is essentially the same as the thoracentesis and can be performed at the bedside. It is necessary, no special additional preparation of the patient. At least three samples from a site on the skin, with 3, 6, and 9 o’clock position of the “needle-cutting chamber” are needed for histology and culture. A chest X-ray should be done after the biopsy, there is an increased risk for complications exists, which are the same as for a thoracentesis, but with a higher incidence of pneumothorax and hemothorax.

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