(Bubonic plague, Pestis; Black Death)

Plague is caused by Yersinia pestis. The symptoms consist of either severe pneumonia or a massive lymphadenopathy with high fever, which often progress to septicemia. The suspected diagnosis is made clinically and epidemiologically and confirmed by the cultural detection of pathogens and serologically. The therapy is performed with streptomycin or gentamicin; Alernativen are a fluoroquinolone or doxycycline.

Yersinia (formerly Pasteurella) pestis is reminded (especially in the Giemsa stain) and located on a safety pin a short rod-shaped bacterium, which stains often bipolar.

Plague is caused by Yersinia pestis. The symptoms consist of either severe pneumonia or a massive lymphadenopathy with high fever, which often progress to septicemia. The suspected diagnosis is made clinically and epidemiologically and confirmed by the cultural detection of pathogens and serologically. The therapy is performed with streptomycin or gentamicin; Alernativen are a fluoroquinolone or doxycycline. Yersinia (formerly Pasteurella) pestis is reminded (especially in the Giemsa stain) and located on a safety pin a short rod-shaped bacterium, which stains often bipolar. Plague occurs primarily in wild rodents before (eg. As rats, mice, squirrels, prairie dogs) and is transmitted by the bite of an infected rat flea (vector) from rodent to humans. The plague can be transmitted through contact with fluid or tissue from an infected animal. To a transmission from human to human it comes through inhalation of infectious droplets of patients with pulmonary infection (especially pneumonic plague), which is highly contagious. In US endemic areas several cases might be caused by pets, especially cats (due to the consumption of infected rodents infected) have been transferred. Transmission by cats, by the bite of an infected flea or, if the cat has pneumonic plague, also take place by inhalation of infectious respiratory droplets. The pneumonic plague can be transmitted through exposure in the laboratory or by intentional aerosol spread as an act of bioterrorism. In earlier centuries there were massive outbreaks in humans (eg. As the Black Death in the Middle Ages, an epidemic in Manchuria in 1911). In modern times, plague occurs only smaller outbreaks sporadically or form. The last outbreak of urban associated with rat plague in the US occurred in Los Angeles from 1924 to 1925. Since then,> 90% of human Pestkrankheiten in the US occur in rural and semi-rural areas of the Southwest, particularly in New Mexico, Arizona, California and Colorado. Symptoms and signs There are several distinct clinical manifestations: Bubonic Plague (most common) pneumonic (primary or secondary) Pestsepsis Pestis minor case of bubonic plague, which is the most common manifestation, the incubation period is usually between 2 and 5 days, but can range from a few hours to vary to 12 days. The fever reaches 39.5 to 41 ° C and begins abruptly, often with chills. The pulse can be accelerated and thready; it may cause a drop in blood pressure. The lymph nodes that drain the site of inoculation by the bacteria are larger and sensitive (buboes) and appear shortly after the fever. Most often the femoral or inguinal lymph nodes are affected, followed by axillary, cervical or other lymph nodes. Characteristically, the lymph nodes are extremely sensitive and hard and surrounded by a considerable edema. In the second week they can fester. The overlying skin is soft and reddened but often not overheated. At the flea bite sometimes occur a primary cutaneous lesion, which may vary between a small bubble with mild local lymphangitis to a scabby crusting. The patient may restless, delirious, seem confused and uncoordinated. Liver and spleen may be enlarged. Because the bacteria can spread through the bloodstream to other parts of the body, the bubonic plague may be complicated by a hematogenous (secondary) pneumonic plague. Pestbeule (thigh) Image courtesy of Drs. Margaret Parsons and Karl F. Meyer Public Health Image Library of the Centers for Disease Control and Prevention. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/plague_bubo_femoral_orig_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/plague_bubo_femoral_orig_high_de.jpg?la = en & thn = 0 ‘, title:’ Pestbeule (thigh) ‘description:’ u003Ca id = “v37895905 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eEin Bubo

Health Life Media Team

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