Under a peptic ulcer is meant an erosion in a segment of the gastrointestinal mucosa, typically in the stomach (gastric ulcers) or a few centimeters in the duodenum (duodenal ulcers), which penetrates into the muscularis mucosae. Almost all ulcers are caused by Helicobacter pylori infection or NSAIDs. The symptoms typically consist of burning epigastric pain subside often after food intake. The diagnosis is made by endoscopy or detection of H. pylori. The treatment includes suppression of acid formation, the eradication of H. pylori (if any), and the avoidance of NSAIDs.

Ulcers can range in size from a few millimeters to a few centimeters. Ulcers are delineated from erosions by the depth of their penetration into the tissue, erosions are superficial and do not relate to the muscularis mucosae. Ulcers can occur at any age, incl. Infants and children, but in adults in middle age the most.

Under a peptic ulcer is meant an erosion in a segment of the gastrointestinal mucosa, typically in the stomach (gastric ulcers) or a few centimeters in the duodenum (duodenal ulcers), which penetrates into the muscularis mucosae. Almost all ulcers are caused by Helicobacter pylori infection or NSAIDs. The symptoms typically consist of burning epigastric pain subside often after food intake. The diagnosis is made by endoscopy or detection of H. pylori. The treatment includes suppression of acid formation, the eradication of H. pylori (if any), and the avoidance of NSAIDs. Ulcers can range in size from a few millimeters to a few centimeters. Ulcers are delineated from erosions by the depth of their penetration into the tissue, erosions are superficial and do not relate to the muscularis mucosae. Ulcers can occur at any age, incl. Infants and children, but in adults in middle age the most. Etiology H. pylori and NSAIDs destroy the defense and repair mechanisms of the mucous membrane and make the mucosa more sensitive to acid. H. pylori infection (Helicobacter pylori infection) is 50-70% of patients with duodenal ulcers and 30-50% of patients with gastric ulcers. After H. pylori eradication occurs only in 10-20% of patients have a recurrence of peptic ulcer disease, compared with a recurrence rate of 70% in patients who were treated with acid-suppressive measures. NSAIDs are now the cause of> 50% of gastric ulcers. Cigarette smoking is a risk factor for the development of ulcers and their complications. In addition, smoking affects healing and increases the rate of recurrence. The risk is directly correlated with the number of cigarettes smoked per day. Although alcohol is basically a potent stimulator of acid secretion, there is no definitive data that can make moderate alcohol consumption for the emergence or delayed healing of ulcers responsible. Very few patients suffering from hypersecretion of gastrin (Zollinger-Ellison syndrome, gastrinoma). At 50-60% of children with duodenal a positive family history is present. Symptoms and signs The symptoms depend on the localization of the ulcer and the age of the patient; many patients v. a. older, have few or no symptoms. The most common is pain, often limited to the epigastrium, he is improved by ingestion or Antazidagabe. The pain was burning or gnawing character, sometimes there is also a feeling of hunger. The course is chronic or recurrent, as a rule. Only about half of patients showing symptoms characteristic pattern. The symptoms during gastric ulcer does not always follow a uniform pattern (food intake sometimes leads to increase and not to decrease in pain). This is also true for ulcers in the pyloric channel, often with a locking symptoms (eg. As bloated upper abdomen, nausea and vomiting) associated on the floor of edema and scarring. Duodenal ulcers show a more constant pain pattern. The pain does not occur when the patient wakes up, but early in the morning, he is relieved by food intake, but is 2-3 h after the meal again. Pain that wakes the patient at night, is always highly suspicious of the existence of a duodenal ulcer. In newborns, a perforation or bleeding may be the first manifestation of a duodenal ulcer. Bleeding can also be the first recognized symptom in early childhood and early youth, his, although repeated vomiting or abdominal pain a strong indication of this are. Diagnostic endoscopy Occasionally serum gastrin gastric ulcers figure provided by David M. Martin, M.D. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/gastric_ulcer_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/gastric_ulcer_high_de.jpg?la = en & thn = 0 ‘, title:’ ulcers ‘description:’ u003Ca id = “v37892510 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eAuf this figure can be seen in the middle of a big Magenulkuskrater. Because of the cancer risk

Health Life Media Team

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