The peliosis hepatis is typically asymptomatic disease, in which multiple blood-filled cystic cavities in the liver develop.

(See also Overview of vascular diseases of the liver.)

The peliosis hepatis is typically asymptomatic disease, in which multiple blood-filled cystic cavities in the liver develop. (See also Overview of vascular diseases of the liver.) The cysts of peliosis hepatis are only a few millimeters up to 3 cm in diameter large, they often lack a limiting cell layer and they are surrounded by hepatocytes. Some have a endothelial lining, accompanied by dilated sinusoids. The reasons are probably damaged Sinusoidalzellen. The peliosis hepatis associated with the administration of hormones (anabolic steroids, oral contraceptives, corticosteroids), tamoxifen, vinyl chloride, Vitamin A and especially after kidney transplantation azathioprine. Peliosis hepatis is usually asymptomatic, but occasionally burst cysts, sometimes leading to bleeding and death. Some patients develop overt liver disease, characterized by jaundice, hepatomegaly and liver failure. Mild cases are often detected during imaging tests, which are carried out due to slightly abnormal liver function tests or for other reasons. Using ultrasound or computed tomography, the cysts can be displayed. Most cases are not treated.

Health Life Media Team

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