Pancreatitis can pull affected both the exocrine and endocrine function of the organ. The pancreatic acinar cells secrete digestive enzymes and bicarbonate into the pancreatic ducts, which ultimately open into the main duct at the papilla into the duodenum (exocrine function). The beta cells of the pancreas secrete insulin directly into the bloodstream (endocrine function).

A distinction is an acute and chronic pancreatitis. Acute pancreatitis is an inflammation that heals both clinically and histologically perfect. Chronic pancreatitis however, is characterized by an irreversible and progressive tissue damage that can lead to a pronounced loss of exocrine and endocrine function. In patients with chronic pancreatitis, acute inflammation episodes occur. Pancreatitis can pull affected both the exocrine and endocrine function of the organ. The pancreatic acinar cells secrete digestive enzymes and bicarbonate into the pancreatic ducts, which ultimately open into the main duct at the papilla into the duodenum (exocrine function). The beta cells of the pancreas secrete insulin directly into the bloodstream (endocrine function).

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