Acute leukemia results from the malignant transformation of a hematopoietic stem cell into a primitive, undifferentiated cell with an abnormally prolonged service life.

This lmphatischen cells (acute lymphocytic leukemia [ALL] – Acute Lymphocytic Leukemia (ALL)) or myeloid cells (acute myeloid leukemia [AML] – Acute myeloid leukemia (AML)) proliferate and displace the normal bone marrow and the hematopoietic cells, whereby in the consequence anemia, thrombocytopenia and granulocytopenia occur. Via the bloodstream, they can infiltrate various organs such as liver, spleen, lymph nodes, kidneys, gonads or the central nervous system.

Acute leukemia results from the malignant transformation of a hematopoietic stem cell into a primitive, undifferentiated cell with an abnormally prolonged service life. This lmphatischen cells (acute lymphocytic leukemia [ALL] – Acute Lymphocytic Leukemia (ALL)) or myeloid cells (acute myeloid leukemia [AML] – Acute myeloid leukemia (AML)) proliferate and displace the normal bone marrow and the hematopoietic cells, whereby in the consequence anemia, thrombocytopenia and granulocytopenia occur. Via the bloodstream, they can infiltrate various organs such as liver, spleen, lymph nodes, kidneys, gonads or the central nervous system. Symptoms and signs The symptoms can occur prior to diagnosis only a few days or weeks. The most common symptoms of disturbed hematopoiesis are anemia, infection and hematoma and bleeding. Other symptoms and complaints are rather non-specific (eg. As pallor, fatigue, fever, malaise, weight loss, tachycardia, chest pain) and a result of anemia or hypermetabolic state. One cause of the fever is often not found. Nevertheless, it may come through the granulocytopenia to a rapidly progressive and potentially life-threatening infection. Bleeding usually show as petechiae, easy bruising, nosebleeds, bleeding gums, and menstrual irregularities. Hematuria, and gastrointestinal bleeding are rare. The bone marrow and Periostinfiltration can cause bone or joint pain, which is particularly common in children with ALL the case. A primary CNS involvement or leukemic meningitis, which can manifest itself through headaches, vomiting, irritability, cranial nerve palsies, seizures and papilledema, is rare. (Editor’s note: Can occur in 3-15%!) The extramedullary infiltration of leukemia cells may result in lymphadenopathy, splenomegaly, hepatomegaly or infiltrates in the skin (raised, nichtjuckende rashes). A gingival hyperplasia can, especially in AML, be present. Leukemia cutis (Isolated) © Springer Science + Business Media var model = {thumbnailUrl: ‘/-/media/manual/professional/images/472-leukemia-cutis-localized-slide-5-springer-high_de.jpg?la=de&thn = 0 & mw = 350 ‘, imageUrl’ /-/media/manual/professional/images/472-leukemia-cutis-localized-slide-5-springer-high_de.jpg?la=de&thn=0 ‘, title:’ leukemia cutis cause u003Ca id = “v37895169 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eLeukämien the skin: (localized) ‘description’ erythematous papules

Health Life Media Team

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