(ON the jaw)

Osteonecrosis of the jaw is an oral lesion, wherein the lower jaw, or the jaw bones are involved. It can cause pain or may be asymptomatic. The diagnosis is made by the presence of exposed bone for at least 8 wk. Treatment is limited debridement, antibiotics and oral rinses.

The osteonecrosis of the jaw has no universally accepted definition or aetiology, but generally it is believed that it is an oral lesion involving the mandible or maxilla.

Osteonecrosis of the jaw is an oral lesion, wherein the lower jaw, or the jaw bones are involved. It can cause pain or may be asymptomatic. The diagnosis is made by the presence of exposed bone for at least 8 wk. Treatment is limited debridement, antibiotics and oral rinses. The osteonecrosis of the jaw has no universally accepted definition or aetiology, but generally it is believed that it is an oral lesion involving the mandible or maxilla. The osteonecrosis of the jaw can spontaneously or after tooth extraction or trauma, radiation therapy to the head and neck (ORN) or a high dose i.v. Bisphosphonate therapy (eg., For treatment of cancer) can occur. When osteonecrosis of the jaw may be a refractory osteomyelitis as a true osteonecrosis rather, especially if it is associated with the use of bisphosphonates. There is no evidence that the routine use of oral bisphosphonates for the treatment or prevention of osteoporosis increases the risk of osteonecrosis of the jaw. from an otherwise displayed application of bisphosphonates currently should not be discouraged. However, it seems reasonable to perform required maxillofacial surgery before beginning bisphosphonate therapy and promote good oral hygiene, while patients taking bisphosphonates (1). ONJ symptoms and complaints can remain asymptomatic for a long time. The symptoms tend usually to develop symptoms, although pain may precede the symptoms. ONJ manifests itself usually with pain and purulent discharge from exposed bone in the mandible or, less commonly, maxilla. Also, teeth and gums may be affected. Intraoral or Extraoral fistula may develop. Diagnosis Clinical Investigation Osteonecrosis of the jaw is diagnosed when an exposed, necrotic bone is present for at least 8 weeks in the upper or lower jaw. Therapy Limited debridement, antibiotics and oral rinses. If the diagnosis is secured, the treatment of osteonecrosis of the jaw challenging and should be done by an oral surgeon with experience in treating this disease. The treatment of ONJ usually involves a limited debridement, antibiotics and mouthwashes (1). Surgical resection of the affected area can worsen the condition and should not be the first treatment measure. Treatment Note 1. Edwards BJ, Hellstein JW, Jacobsen PL, et al: Updated recommendations for managing the care of patients receiving oral bisphosphonate therapy: An advisory statement from the American Dental Association Council on Scientific Affairs. J Am Dent Assoc 139: 1674-1677., 2008

Health Life Media Team

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