(Carrion’s disease)

Oroyafieber and Verruga peruana are caused by Bartonella bacilliformis infections. The Oroyafieber occurs after an initial exposure; a Verruga peruana occurs after the healing of the primary infection.

(See also overview of infections caused by Bartonella.)

Oroyafieber and Verruga peruana are caused by Bartonella bacilliformis infections. The Oroyafieber occurs after an initial exposure; a Verruga peruana occurs after the healing of the primary infection. (See also overview of infections caused by Bartonella.) Both Oroya fever and Verruga Peruana are endemic only in the Andes in Colombia, Ecuador and Peru and the genus Phlebotomus are transmitted from person to person through sand flies. Oroyafieber The symptoms of Oroya fever is characterized by fever and severe anemia, which can be sudden or gradual occur. It is primarily a hemolytic anemia, but myelosuppression comes just before. Muscle and joint pain, severe headache and often delirium and coma can occur. Likewise, to aufpfropfende fact caused by Salmonella or other coliforms bacteremia may occur. The mortality rate can be in untreated patients over 50%. The diagnosis of Oroya fever is confirmed by blood cultures. Because Oroyafieber is often ierschwert by Salmonella bacteremia, chloramphenicol is 500-1000 mg po every 6 h the treatment of choice for 7 days; some doctors take another antibiotic, typically doxycycline or a beta-lactam added, but trimethoprim / sulfamethoxazole (TMP / SMX), macrolides and fluoroquinolones have also been used successfully. Verruga peruana Verruga peruana manifests itself in the form of multiple skin lesions that are strongly reminiscent of a bacillary angiomatosis; these elevated, reddish-purple skin nodules usually appear on the limbs and face. The lesions may persist for months to years and accompanied by pain and fever. A Verruga peruana is diagnosed primarily clinical, sometimes by biopsy showing a dermal angiogenesis. The treatment with most antibiotics leads to remission but relapses are common and require prolonged therapy. The typical treatment is carried out with rifampin 10 mg / kg p.o. once / day for 10 to 14 days or streptomycin 15 to 20 mg / kg i.m. once / day for 10 days. Ciprofloxacin 500 mg p.o. 2 times daily for 7-10 days has been successfully used as azithromycin, doxycycline and trimethoprim-sulfamethoxazole.

Health Life Media Team

Leave a Reply