Onchocerciasis is a filarial infections (overview of filarial infections) with Onchocerca volvulus. The symptoms consist of subcutaneous nodules, pruritus, rash, adenopathy, obstruction of lymphatic vessels and eye lesions that can lead to blindness. The diagnosis is made by the detection of microfilaria in skin biopsies, the cornea or the anterior chamber, through the detection of adult worms in the node subcutaneous or by PCR-based DNA detection. Treatment is with ivermectin.

Onchocerciasis is a filarial infections (overview of filarial infections) with Onchocerca volvulus. The symptoms consist of subcutaneous nodules, pruritus, rash, adenopathy, obstruction of lymphatic vessels and eye lesions that can lead to blindness. The diagnosis is made by the detection of microfilaria in skin biopsies, the cornea or the anterior chamber, through the detection of adult worms in the node subcutaneous or by PCR-based DNA detection. Treatment is with ivermectin. Pathophysiology Onchocerciasis is blackflies ( “black flies”, Simulium sp.) Spread that breed in fast-flowing rivers (hence the term river blindness). By the bite of the black fly infective larvae are inoculated into the skin that develop within 12-18 months to adult worms. Adult female worms can live in node subcutaneous up to 15 years. The females are 33-50 cm long, the males 19-42 mm. Mature female worms produce microfilariae that migrate mainly through the skin and infected eyes. Life Cycle of Onchocerca volvulus. Picture of the Centers for Disease Control and Prevention Image Library. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/onchocerca_volvulus_life_cycle_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/onchocerca_volvulus_life_cycle_high_de.jpg?la = en & thn = 0 ‘, title:’ life cycle of Onchocerca volvulus ‘description:’. u003cdiv class = “list ” u003e u003cul data-mmanualobjecttype = “”list “” class = “”nobulleted “” u003e u003cli u003e u003Ca id = “”v1013711_de “” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003e1. During a blood meal

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