Melanoma

(Malignant melanoma)

Malignant melanomas go from the melanocytes in pigmented areas of (eg., Skin, mucous membranes, eyes or CNS). The risk of metastasis correlated with the depth of dermal invasion. In chain stores, the prognosis is poor. The diagnosis is made by biopsy. In operable tumors is the generous excision treatment of choice. The metastatic disease is treated with systemic therapy, however, is difficult to cure.

Every year about 76,250 new melanoma disease in the U.S.A. occur, leading to about 9,180 deaths. The lifetime risk is about 1-2%. The incidence has remained stable over the last 8 years (they had previously been increasing at a faster rate than any other malignant tumors). <5% of the total diagnosed in the US skin cancers are melanomas; However, they have the highest morbidity of all skin cancers. On average, every hour a person dies in the United States of melanoma.

Malignant melanomas go from the melanocytes in pigmented areas of (eg., Skin, mucous membranes, eyes or CNS). The risk of metastasis correlated with the depth of dermal invasion. In chain stores, the prognosis is poor. The diagnosis is made by biopsy. In operable tumors is the generous excision treatment of choice. The metastatic disease is treated with systemic therapy, however, is difficult to cure. Every year about 76,250 new melanoma disease in the U.S.A. occur, leading to about 9,180 deaths. The lifetime risk is about 1-2%. The incidence has remained stable over the last 8 years (they had previously been increasing at a faster rate than any other malignant tumors). <5% of the total diagnosed in the US skin cancers are melanomas; However, they have the highest morbidity of all skin cancers. On average, every hour a person dies in the United States of melanoma. Melanomas occur mainly on the skin, but also on the mucous membrane of the mouth, genital and rectal area and the conjunctiva. Melanoma can also, in the choroid of the eye with leptomeningeal ( "pia" or "arachonid") and develop in the nail bed. Melanomas differ in size, shape and color (usually pigmented) as well as their tendency to invasive growth and metastasis. Metastases spread through the lymphatic and blood vessels. Satellite metastases occur. Also direct metastasis in skin and internal organs are possible. Metastases can spread on the skin and internal organs; occasionally the metastatic nodules or enlarged lymph nodes are discovered before the primary lesion. Malignant melanoma (non-sun-exposed area) © Springer Science + Business Media var model = {thumbnailUrl: '/ - / media / manual / professional / images / 449-malignant-melanoma-nonsun-exposed-area-slide-23-springer ? lang = en & -high_de.jpg thn = 0 & mw = 350 ', imageUrl:' /-/media/manual/professional/images/449-malignant-melanoma-nonsun-exposed-area-slide-23-springer-high_de.jpg? lang = en & thn = 0 ', title:' Malignant melanoma (non-sun-exposed area) ', description:' u003Ca id = "v37894599 " class = ""anchor "" u003e u003c / a u003e u003cdiv class = ""para "" u003e u003cp u003eMalignes melanoma of the vulva u003c / p u003e u003c / div u003e with focal enlargement of the urethral opening . 'credits' © Springer Science + Business Media'

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