Medullary Sponge Kidney

Under medullary sponge kidney is the formation of diffuse bilateral Mark cysts caused by abnormalities in the terminal collecting ducts.

(See also Overview of cystic Nierenerkrankheiten.)

Under medullary sponge kidney is the formation of diffuse bilateral Mark cysts caused by abnormalities in the terminal collecting ducts. (See also Overview of cystic Nierenerkrankheiten.) The cause of medullary sponge kidney is unknown, but genetic transmission occurs in <5% of the cases. Most patients are asymptomatic, and the disorder usually remains undiagnosed. You scheduled to stone formation (often with an increased calcium excretion) and UTI, so that the most common symptoms are: renal colic hematuria dysuria The medullary sponge kidney is benign and the long-term prognosis is good. Obstruction by kidney stones may temporarily reduce the glomerular filtration rate (GFR) and let rise serum creatinine. Diagnostic CT or IVU The diagnosis is suspected in patients with recurrent UTI or stone formation or, on the basis of random radiological findings as medullary nephrocalcinosis and dilated contrast filled collecting ducts. Urinalysis typically shows signs of incomplete distaltubulären acidosis (a general metabolic acidosis is rare) and decreased urine concentration in patients without symptomatic polyuria. The diagnosis is usually confirmed by CT, but IVU can also be used. An ultrasound is not useful because the cysts are small and deep lie in the renal medulla. Therapy control of complications (eg. As urinary tract infections, kidney stones) A ??therapy is indicated only for UTI and in repeated rock formations. Thiazide diuretics (eg. As hydrochlorothiazide, 25 mg po 1 times a day) and increased fluid intake can prevent stone formation by reducing calcium excretion in the urine and prevent urinary. These effects can prevent obstructive complications in patients with recurrent stone formation.

Health Life Media Team

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