Liver Metastases

Metastases of the liver are found in many cancers, v. a. those of the gastrointestinal tract, breast, lung and pancreas. The first symptoms of metastases are generally non-specific (eg. As weight loss, pain in the right upper abdomen), sometimes they are the first symptoms of the primary tumor. The suspicion of liver metastases, patients with weight loss and hepatomegaly, or primary tumors that can easily spread to the liver. The diagnosis is usually supported by imaging methods, most commonly by contrast-enhanced ultrasound, spiral computed tomography with contrast or MRI with contrast. Treatment often includes palliative chemotherapy.

Metastases of the liver are more common than primary liver cancer. They are sometimes the first manifestation of a cancer in the gastrointestinal tract, breast, lung or pancreas.

Metastases of the liver are found in many cancers, v. a. those of the gastrointestinal tract, breast, lung and pancreas. The first symptoms of metastases are generally non-specific (eg. As weight loss, pain in the right upper abdomen), sometimes they are the first symptoms of the primary tumor. The suspicion of liver metastases, patients with weight loss and hepatomegaly, or primary tumors that can easily spread to the liver. The diagnosis is usually supported by imaging methods, most commonly by contrast-enhanced ultrasound, spiral computed tomography with contrast or MRI with contrast. Treatment often includes palliative chemotherapy. Metastases of the liver are more common than primary liver cancer. They are sometimes the first manifestation of a cancer in the gastrointestinal tract, breast, lung or pancreas. Symptoms and signs Early liver metastases may be asymptomatic. Non-specific symptoms of cancer (eg. As weight loss, loss of appetite, fever) often occur first. The liver may be increased to be hard and painful to pressure; a massive hepatomegaly with palpable nodes easily displays an advanced disease. Noise of the liver and a pleuratypischer pain with a friction sound are unusual, but characteristic. Occasionally, splenomegaly, v. a. if the primary cancer is located in the pancreas. Simultaneous peritoneal tumor seeding can lead to the formation of ascites, jaundice is not or is usually initially not very pronounced when the tumor has not led to biliary obstruction. In the terminal stages of a progressive jaundice and hepatic encephalopathy are sign of approaching death. Diagnostic ultrasound, computed tomography or MRI with contrast Sometimes biopsy Suspicion of liver metastases arises in patients with weight loss and hepatomegaly, or in patients with primary tumors often spread to the liver. If the suspicion of metastasis is the liver values ??are often determined, although they are usually not specific for the diagnosis. The values ??for transaminases vary. Alkaline phosphatase, gamma GT and sometimes LDH rise sooner or to a greater extent than the other liver function tests. Imaging methods have good sensitivity and specificity. Ultrasound contrast agent is usually helpful, but computed tomography with contrast or MRI with contrast is often more accurate. Metastatic liver Image courtesy of Patrick O’Kane, M.D. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/metastatic_liver_cancer_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/metastatic_liver_cancer_high_de.jpg?la = en & thn = 0 ‘, title:’ metastases of the liver ‘, description:’ u003Ca id = “v37892705 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDas pathological thoracic MRI shows areas with low shading (marked with arrows) in the liver. This picture is typical of metastatic liver u003c / p u003e u003c / div u003e ‘credits’. Image courtesy of Patrick O’Kane

Health Life Media Team

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