Lincosamides, Oxazolidinones And Streptogramins

Cross resistance occurs under the following antibiotics because they have a binding to the same target structure:

Lincosamides (clindamycin clindamycin), oxazolidinones (linezolid, Tedizolid- linezolid and Tedizolid), streptogramins (dalfopristin [streptogramin A] and quinupristin [streptogramin B] – quinupristin and dalfopristin) are grouped together because of similar antibacterial mechanism of action and the comparable antibacterial spectrum. Macrolides (macrolides), and the ketolide telithromycin (telithromycin) can be classified into this group for similar reasons. All inhibit protein synthesis by binding to the 50S ribosomal subunit. Cross resistance occurs under the following antibiotics because they have a binding to the same target structure: macrolides, clindamycin quinupristin telithromycin (to some extent) However, it does not lead to cross-resistance between these antibiotics and dalfopristin or linezolid, the different target structures of the 50S subunit of the ribosome binding.

Health Life Media Team

Leave a Reply