Lichen Planus

planus Lichen is a recurrent, itchy, inflammatory rash with small, discreet, polygonal, flattened, livid papules that may coalesce, often are also oral and / or genital lesions before. The diagnosis is usually made clinically and secured by means of skin biopsy. Glucocorticoids are administered topically or intralesionally to treat. In severe cases phototherapy or systemic glucocorticoids, retinoids or immunosuppressive agents is often required.

planus Lichen is a recurrent, itchy, inflammatory rash with small, discreet, polygonal, flattened, livid papules that may coalesce, often are also oral and / or genital lesions before. The diagnosis is usually made clinically and secured by means of skin biopsy. Glucocorticoids are administered topically or intralesionally to treat. In severe cases phototherapy or systemic glucocorticoids, retinoids or immunosuppressive agents is often required. Etiology probably arises lichen planus in patients with genetic predisposition by a T-cell mediated autoimmune reaction against the basal epithelial keratinocytes. Drugs (v. A. ?-blockers, NSAID, ACE inhibitors, sulfonylureas, gold, antimalarials, penicillamine and thiazides) can cause LP. The drug-induced LP (sometimes referred to as lichenoid drug eruption) often can not be distinguished from the non-drug-related form, or may extend more eczematous. Correlations with hepatitis (hepatitis B infection, hepatitis B vaccine, and especially hepatitis C-induced liver failure), primary biliary cirrhosis, and other forms of hepatitis were reported. Symptoms and complaints as typical lesions appear itchy, purple, polygonal, flattened papules and plaques. Initial lesions have a diameter of 2-4 mm, an angular edge, a violet color and shine like varnish. They are usually distributed symmetrically, occur predominantly on the flexor surfaces of the wrists and legs, trunk, on the glans penis and on the oral and vaginal mucosa, but may also be disseminated. The face is rarely affected. The outbreak may occur abruptly or gradually. Children are rarely affected. During the acute phase, new papules often occur in areas with minor skin injuries (Koebner phenomenon) such. B. superficial scratches. Over time may merge the lesions or change, hyperpigmentieren, atrophy, hyperkeratotic (lichen planus hypertrophicus) or vesikulobullös. Although the lesions itchy, but are rarely excoriated or crusted. For infestation of the scalp is a mottled, scarring alopecia may develop (lichen planus follicularis). Lichen planus (skin) figures provided by Thomas Habif, M.D. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/lichen_planus_skin_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/-/media/manual/professional/images/lichen_planus_skin_high_de.jpg?la = en & thn = 0 ‘, title:’ Lichen planus (skin) ‘description:’ u003Ca id = “v37895005 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eDie lesions in Lichen planus are itchy papules (top) or plaques (below)

Health Life Media Team

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