Korsakoff’S Psychosis

(Korsakoff’s amnesic syndrome, Korsakoff’s psychosis)

The Korsakoff’s psychosis is a late complication of persistent Wernicke encephalopathy, which leads to impaired memory, confabulations, confusion and behavioral changes.

In 80% of untreated patients with Wernicke encephalopathy, a Korsakoff’s psychosis occurs. Severe alcoholism is a common underlying disease. It is not yet clear why a Korsakoff’s psychosis developed only in some patients with Wernicke’s encephalopathy. tremens a heavy or repeated Delirium can trigger a Korsakoff’s psychosis, regardless of whether a typical Wernicke encephalopathy is preceded.

The Korsakoff’s psychosis is a late complication of persistent Wernicke encephalopathy, which leads to impaired memory, confabulations, confusion and behavioral changes. In 80% of untreated patients with Wernicke encephalopathy, a Korsakoff’s psychosis occurs. Severe alcoholism is a common underlying disease. It is not yet clear why a Korsakoff’s psychosis developed only in some patients with Wernicke’s encephalopathy. tremens a heavy or repeated Delirium can trigger a Korsakoff’s psychosis, regardless of whether a typical Wernicke encephalopathy is preceded. Other triggers include subarachnoid hemorrhage, Thalamusblutung, Thalamusinfarkt and rare tumors of the paramedian posterior thalamus (traumatic brain injury (TBI)). Symptoms and complaints Short-term memory is severely impaired; it comes in varying degrees to retrograde and anterograde amnesia. Patients can recall long past events usually; So long-term memory seems to be less affected than short-term memory. Usually there is a temporal disorientation and emotional changes. These include apathy, flatness or mild euphoria with little or no responsiveness to environmental stimuli, even anxiety-provoking situations. Spontaneity and initiative may be limited. Confabulations are often a particularly striking early symptom. The confused patients fill while their memory lapses unconsciously fantasized events on. This fantasy can sometimes be so compelling that the underlying disease remains undetected. Diagnosis Clinical examination Diagnosis is based on the typical symptoms in patients with a known severe chronic Alkoholabhängigkei. Other causes of symptoms (eg. As CNS injury or infection) must be excluded. Thiamine and therapy supportive care, the treatment consists of elimination of thiamine deficiency and adequate hydration.

Health Life Media Team

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