Iron (Fe) is a component of hemoglobin, myoglobin and many enzymes. Heme iron, which is mainly contained in animal foods, is better absorbed than non-heme iron (eg. As in plants and cereals), which represents over 85% of the iron to a normal diet. The absorption of non-heme iron can be increased if it is taken with animal protein and Vitamin C. Iron deficiency Iron deficiency is the world’s most common mineral deficiency. Iron deficiency can arise from: inadequate iron intake, which is common among infants, adolescent girls and pregnant women, malabsorption (eg celiac disease.), Chronic bleeding, including heavy menstrual bleeding and gastrointestinal lesions. induced colon cancer chronic bleeding include in middle-aged and elderly to the causes of iron deficiency. In severe deficiency a microcytic anemia develops. Iron deficiency can cause anemia except lead to pica (eating inedible substances) and spoon nails and is associated with restless legs syndrome. Rarely causes iron deficiency dysphagia web due to esophageal postcricoid. The diagnosis of iron deficiency include CBC, serum ferritin and iron levels and optionally measuring the transferrin saturation (iron binding capacity). At deficiency of iron and ferritin levels are rather low and the iron binding capacity is rather high. All people with moderate or severe iron deficiency and some people with mild deficiency need an iron supplement. Iron Toxicity iron accumulates in the body to: excessive and long intake of iron in a iron therapy repeated blood transfusions chronic alcoholism overdose of iron Iron overload can also be attributed to a congenital disease be (hemochromatosis), a potentially fatal, but good to be treated genetically related disorder, is absorbed through the too much iron. More than one million US citizens are affected by hemochromatosis. An overdose of iron is toxic and causes vomiting, diarrhea, and damage to the intestine and other organs. The diagnosis of iron toxicity is similar to iron deficiency. The treatment of iron toxicity often consists in the administration of deferoxamine that binds to iron and is excreted in the urine.