Infections And Serratia – Klebsiella – Enterobacter

Klebsiella, Enterobacter and Serratia are closely related members of the physiological intestinal flora, which rarely result in normal hosts to disease.

Infection with Klebsiella, Enterobacter and Serratia are often acquired nosocomial and occur with reduced resistance to disease, especially in patients. Most Klebsiella, Enterobacter, and Serratia cause a variety of infections, including bacteremia, postoperative wound infections, intravascular catheter infections and infections of the respiratory or urinary tract infections that manifest as pneumonia, cystitis or pyelonephritis and develop into lung abscesses, empyema, bacteremia and sepsis can, as follows:

Klebsiella, Enterobacter and Serratia are closely related members of the physiological intestinal flora, which rarely result in normal hosts to disease. Infection with Klebsiella, Enterobacter and Serratia are often acquired nosocomial and occur with reduced resistance to disease, especially in patients. Most Klebsiella, Enterobacter, and Serratia cause a variety of infections, including bacteremia, postoperative wound infections, intravascular catheter infections and infections of the respiratory or urinary tract infections that manifest as pneumonia, cystitis or pyelonephritis and develop into lung abscesses, empyema, bacteremia and sepsis can, as in the following: a Klebsiella pneumonia is a rare and serious illness with dark brown or johannisbeergeleeartigem sputum, Lungenabszessbildung and empyema, most commonly found among diabetics and alcoholics. Serratia, especially S. marcescens has a greater affinity for the urinary tract. Enterobacter infections caused most frequently nosocomial, but can otitis media cause cellulite and neonatal sepsis. Antibiotics based on the results of susceptibility testing Treatment is with cephalosporins of the third generation, cefepime, carbapenems, fluoroquinolones, piperacillin / tazobactam or aminoglycosides. However, as some isolates are resistant to multiple antibiotics, sensitivity testing is required. Klebsiella strains producing extended spectrum beta-lactamase (ESBL), can develop resistance to cephalosporins during treatment, particularly with ceftazidime; ESBL these strains are in variable degree by beta-lactamase inhibitors (eg. B. sulbactam, tazobactam, clavulanate) inhibited. Carbapenemase-producing species of K. pneumoniae (KPC) have been isolated internationally and in the US, which makes the treatment of some infections very problematic. Ceftazidime / Avibactam (a new beta-lactamase inhibitor) has activity against KSK isolates. Enterobacter strains may be resistant to most beta-lactam antibiotics, including third-generation cephalosporins; the beta-lactamase enzyme which they produce is not inhibited by the usual betalactamase inhibitors (clavulanic acid, tazobactam sulbactam). However, these strains Enterobacter can be prone to carbapenems (e. As imipenem, meropenem, ertapenem). Carbapenemase-resistant Enterobacteriaceae have also been discovered. In certain cases, ceftazidime / Aviabactam, tigecycline and colistin possibly may be the only available active antibiotics.

Health Life Media Team

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