Incipient Ovarian Failure (Dor)

An incipient ovarian failure means a reduced quantity or quality of the oocytes, which fertility is impaired.

The functioning of the ovaries usually begins at the age of 30 years or even subside earlier and fades quickly after age 40. Also reduce injuries ovarian operability. Although older age is a risk factor for ovarian failure, both the age and ovarian failure are independent predictors of infertility and thus a worse response to the sterility treatment.

An incipient ovarian failure means a reduced quantity or quality of the oocytes, which fertility is impaired. The functioning of the ovaries usually begins at the age of 30 years or even subside earlier and fades quickly after age 40. Also reduce injuries ovarian operability. Although older age is a risk factor for ovarian failure, both the age and ovarian failure are independent predictors of infertility and thus a worse response to the sterility treatment. Diagnosis FSH and estradiol levels, sometimes after stimulation with clomiphene Anti-Müllerian hormone (AMH) levels and Antralfollikelzahl (AFC) Testing for decreased ovarian reserve is drawn to women considered that are ? 35 Had ovarian surgery Insufficiently have responded to therapy such as ovarian stimulation with exogenous gonadotropins. Levels of follicle stimulating hormone (FSH)> 10 mI.E./ml or estradiol <80 pg / ml on day 3 of the menstrual cycle suggest the diagnosis. can be secured the diagnosis by the patient clomiphene 100 mg po 1 time / day of 5-9th The cycle is (clomiphene load test); after FSH and estradiol levels are measured again. A dramatic increase in FSH and estradiol levels of 3-10th The cycle can then detect ovarian failure. The AMH levels is an early, reliable indication of an incipient ovarian failure. Increasingly, the AMH determination to assess the functional capability of the ovary is used. A low AMH levels predicts a lower chance of pregnancy after in vitro fertilization (IVF); to pregnancy it is rare when the level is below the detection limit. The AFC is the number of 2-10 mm (mean diameter) large follicles in both ovaries during the early follicular phase; the AFC is determined by observing the ultrasound. If the AFC low (3-10), a pregnancy after IVF is less likely. Sometimes treatment using donor eggs because pregnancy may still be possible for the treatment of ovarian reserve is individually adapted to the circumstances of the woman and the age. For women> 42 years of age or ovarian failure in some cases assisted reproductive using Spenderoozyten is required.

Health Life Media Team

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