Immunoglobulin-A-Associated Vasculitis (Igav)

(Henoch-Schonlein purpura)

The immunoglobulin-A-associated vasculitis (Ivormals Henoch-Schonlein purpura) is a vasculitis that mainly affects small vessels and most commonly affects children. Common manifestations include palpable purpura, arthralgia, gastrointestinal symptoms, and glomerulonephritis. The diagnosis is made clinically in children in general, but requires in adults a biopsy. The disease is self-limiting rule. Corticosteroids can relieve symptoms arthralgia and gastrointestinal, but does not affect the disease process. A progressive glomerulonephritis may require high doses of corticosteroids and cyclophosphamide.

IgA-containing immune complexes are deposited in the small vessels of the skin and in other locations. Possible triggering antigens are viral pathogens that cause infections of the upper respiratory tract and streptococcal infections, medicines, foods, insect bites and vaccinations. A typical little lesion is focal segmental proliferative glomerulonephritis.

The immunoglobulin-A-associated vasculitis (Ivormals Henoch-Schonlein purpura) is a vasculitis that mainly affects small vessels and most commonly affects children. Common manifestations include palpable purpura, arthralgia, gastrointestinal symptoms, and glomerulonephritis. The diagnosis is made clinically in children in general, but requires in adults a biopsy. The disease is self-limiting rule. Corticosteroids can relieve symptoms arthralgia and gastrointestinal, but does not affect the disease process. A progressive glomerulonephritis may require high doses of corticosteroids and cyclophosphamide. IgA-containing immune complexes are deposited in the small vessels of the skin and in other locations. Possible triggering antigens are viral pathogens that cause infections of the upper respiratory tract and streptococcal infections, medicines, foods, insect bites and vaccinations. A typical little lesion is focal segmental proliferative glomerulonephritis. Symptoms and signs The disease begins with a sudden palpable purpura, typically on the feet, legs and, occasionally, the trunk and arms. Purpura begins in small urticarial districts that are palpable and sometimes haemorrhagic and confluent. Smaller Läsionsgruppen may be added over days or weeks. Many patients also have fever and polyarthralgia with periarticular pain and swelling of the ankles, knees, hips, wrists and elbows. Immunoglobulin-A-associated vasculitis (Henoch-Schonlein purpura) DR P. MARAZZI / SCIENCE PHOTO LIBRARY var model = {thumbnailUrl: ‘/ – / media / manual / professional / images / m2400246-Henoch-Schonlein purpura-science photo- ? -library-high_de.jpg lang = en & thn = 0 & mw = 350 ‘, imageUrl:’ /-/media/manual/professional/images/m2400246-henoch-schonlein-purpura-science-photo-library-high_de.jpg?la= de & thn = 0 ‘, title:’ immunoglobulin-A-associated vasculitis (Henoch-Schonlein purpura), ‘description’ u003Ca id = “v37892965 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eErythematöser papular rash on the legs of patients with immunoglobulin-A-associated vasculitis u003c / p u003e u003c / div u003e. ‘credits’ DR P. MARAZZI / SCIENCE PHOTO LIBRARY ‘

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