Hyperhomocysteinemia

Hyperhomocysteinemia may favor the development of arterial and venous thrombosis.

Hyperhomocysteinemia may favor the development of arterial and venous thrombosis.

(See also Thrombotic diseases at a glance.) Hyperhomocysteinemia may favor the development of arterial and venous thrombosis. When hyperhomocysteinemia the risk of arterial and venous thrombosis is likely to increase over a violation of the vascular endothelium. However, some experts believe that there is no definitive sufficient evidence that hyperhomocysteinemia is associated with thrombosis. When homozygous Cystationin beta-synthase deficiency homocysteine ??levels are increased by the over 10-fold. Smaller increases occur in heterozygous deficiency or other changes in folate metabolism, including the methyl tetrahydrofolate dehydrogenase deficiency. The most common causes of hyperhomocysteinemia are acquired deficiency of folate Vitamin B12 Vitamin B6 (pyridoxine) A folate deficiency often occurs because of the Folatanreicherung of wheat flour in the Western world. The abnormality is detected by measuring the levels of homocysteine ??in plasma. Therapy Nutritional Supplements Homocysteine ??levels in plasma can be normalized by the additional administration of folate, vitamin B12 or vitamin B6 alone or in combination. However, it has not been shown whether this also leads to a reduction in the risk of arterial or venous thrombosis.

Health Life Media Team

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