Herpes Simplex Virus Infection In Newborns

A neonatal infection with the herpes simplex virus takes place usually during childbirth. A typical symptom is the vesicular eruption which may be accompanied by a spreading disease or become one. Diagnosis is by viral culture, PCR, immunofluorescence or electron microscopy. Treatment involves a very high parenteral administration of acyclovir and symptomatic treatment.

A neonatal infection with the herpes simplex virus takes place usually during childbirth. A typical symptom is the vesicular eruption which may be accompanied by a spreading disease or become one. Diagnosis is by viral culture, PCR, immunofluorescence or electron microscopy. Treatment involves a very high parenteral administration of acyclovir and symptomatic treatment.

(Herpes simplex virus infection (HSV).) A neonatal infection with the herpes simplex virus takes place usually during childbirth. A typical symptom is the vesicular eruption which may be accompanied by a spreading disease or become one. Diagnosis is by viral culture, PCR, immunofluorescence or electron microscopy. Treatment involves a very high parenteral administration of acyclovir and symptomatic treatment. The herpes simplex virus infection of the newborn has a high mortality and significant morbidity. The incidence is estimated at 1 / 3,000 to 1 / 20,000 live births. HSV type 2 causes more cases than HSV type 1. HSV is usually transmitted during childbirth during the passage of the newborn through the infected birth canal. In some cases, the infection is transplacental or spread from one child to another, by hospital staff or family. Mothers of newborns with HSV infection often have a recently acquired genital infection, but many at the time of birth no apparent history or symptoms of acute genital infection. Symptoms The disease manifests itself usually 1 to 3 weeks of age, but the first symptoms may only appear in the 4th week in rare cases. Newborns can have local findings or disseminated history. Vesicular lesions occur in 70% of cases and are common in both forms. Newborns without local skin lesions usually show local CNS infections. In newborns with isolated skin lesions or mucosal affections it comes untreated often within 7-10 days to a progressive or severe course. Herpes simplex virus infection in neonates with permission of the publisher. From Demmler G .: Congenital and perinatal infections. In Atlas of Infectious Diseases: Pediatric Infectious Diseases. Edited by C. M. Wilfert. Philadelphia, Current Medicine, 1998. var model = {thumbnailUrl: ‘/-/media/manual/professional/images/neonatal_herpes_simplex_infection_high_de.jpg?la=de&thn=0&mw=350’ imageUrl: ‘/ – / media / manual / professional / images / neonatal_herpes_simplex_infection_high_de.jpg lang = en & thn = 0 ‘, title:’? herpes simplex virus infection in newborns ‘description:’ u003Ca id = “v37897790 ” class = “”anchor “” u003e u003c / a u003e u003cdiv class = “”para “” u003e u003cp u003eGruppiert standing vesicles on erythematous bases are characteristic and occur on almost any part of the body u003c / p u003e u003c / div u003e ‘credits.: ‘with permission of the publisher. From Demmler G .: Congenital and perinatal infections. In Atlas of Infectious Diseases: Pediatric Infectious Diseases. Edited by C. M. Wilfert. Philadelphia

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