Hepatitis D

Hepatitis D is caused by a defective RNA virus ( “Delta-agent”), which replicates only in the presence of the hepatitis B virus. It happens with acute HBV infection or as superinfection in chronic HBV infection as a co-infection.

See also causes of hepatitis and overview of the acute viral hepatitis.)

Hepatitis D is caused by a defective RNA virus ( “Delta-agent”), which replicates only in the presence of the hepatitis B virus. It happens with acute HBV infection or as superinfection in chronic HBV infection as a co-infection. See also causes of hepatitis and overview of the acute viral hepatitis.) Hepatitis D is usually transmitted through parenteral or mucous membrane contact with infected blood or body fluids. The infected hepatocytes contain Delta particles of hepatitis B surface antigens (HBsAg) are surrounded. The prevalence of hepatitis D virus (HDV) is geographically different, with epidemic nests in several countries. Intravenous drug abuse is a relatively high risk; HDV is not widespread in contrast to hepatitis B virus (HBV) in the gay scene. Symptoms and signs Acute hepatitis D infection typically manifests as unusually severe acute HBV infection (coinfection) An acute exacerbation of chronic HBV carriers (superinfection) A relatively aggressive course of chronic HBV infection diagnosis Serological tests should therefore be in the initial diagnosis an acute hepatitis viral hepatitis are differential diagnosis, distinguished from other diseases that cause jaundice (Simplified approach to diagnostic potential acute viral hepatitis.). If an acute viral hepatitis is suspected, the following tests to screen for hepatitis viruses A, B and C are carried out: IgM antibody to hepatitis A virus (anti-HAV) hepatitis B surface antigen (HBsAg) IgM antibodies against hepatitis B core (anti-HBc IgM) antibody to hepatitis C virus (anti-HCV) If serological tests for hepatitis B confirm infection and clinical manifestations are serious, should antibodies to HDV (anti-HDV) levels are measured. Anti-HDV is an active infection. Sometimes it is positive until weeks after the acute illness. Therapy Supportive treatment No specific treatment softens the course of acute hepatitis, including hepatitis D Alcohol should be avoided because it increases the liver damage. Restrictions in diet or physical activity incl. The often prescribed bed rest have no scientific basis. Most patients can resume safe to work after the jaundice has subsided, even if the transaminases are still increased. In the cholestatic hepatitis, the administration of cholestyramine can be 8 g p.o. 1 to 2 times reduce the itching daily. Preventive vaccines for immunoprophylaxis of hepatitis D do not exist. The prevention of HBV infection also means an HDV prevention. Important points hepatitis D virus only occurs with existing hepatitis B. Suspect hepatitis D especially when cases of hepatitis B are difficult or if worsen the symptoms of chronic hepatitis B. Treatment and prevention of infections such as hepatitis B.

Health Life Media Team

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