Hemosiderosis

Hemosiderosis is a focal iron deposition that does not lead to tissue damage.

A local hemosiderosis may occur as a result of blood flow within an organ. The iron is released from the erythrocytes, which are leaked from the vascular system, and stored in the affected organ. In this way, significant hemosiderin deposits can develop. Occasionally, the iron loss due to tissue leads to bleeding of iron deficiency anemia, since the leaked into the tissues iron can not be recycled.

Hemosiderosis is a focal iron deposition that does not lead to tissue damage. A local hemosiderosis may occur as a result of blood flow within an organ. The iron is released from the erythrocytes, which are leaked from the vascular system, and stored in the affected organ. In this way, significant hemosiderin deposits can develop. Occasionally, the iron loss due to tissue leads to bleeding of iron deficiency anemia, since the leaked into the tissues iron can not be recycled. Usually the lung is affected. The cause is usually repeated pulmonary hemorrhage; they will contact either idiopathic to (z. B. Goodpasture’s syndrome) or chronic pulmonary hypertension (z. B. as a result of primary pulmonary hypertension, pulmonary fibrosis, severe mitral stenosis) are caused. In addition, there is an accumulation in the kidneys, where hemosiderosis by excessive intravascular hemolysis may be caused. Free hemoglobin is filtered in the glomeruli, which iron is deposited in the kidneys. The renal parenchyma itself is not damaged, but a heavy hemosiderinuria can lead to iron deficiency.

Health Life Media Team

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