For more information, s. Hib Vaccine ACIP Recommendations. Preparations These vaccines are prepared from the purified capsular polysaccharide of Haemophilus influenzae type b (Hib). All Hib vaccines use polyribosylribitol phosphate (PRP) as its polysaccharide, but four different protein carriers are used in the four different Hib conjugate vaccines: diphtheria toxoid (PRP-D) Neisseria meningitidis outer membrane protein (PRP-OMP) tetanus toxoid (PRP-T) diphtheria CRM197 carrier protein mutants (HbOC) PRP-D and HbOC vaccines are no longer available in the US. For the combination vaccines that include Hib-conjugate vaccine include DTaP-IPV / Hib (Pentacel®) Hib-HepB (COMVAX®) and Hib-MenCY (MenHibrix®). Some Hib vaccines PRP-T (ActHIB®, Pentacel® or MenHibrix®) and PRP-OMP (PedvaxHIB® or COMVAX®) -can be used in infants aged 6 weeks. Another Hib vaccine (Hiberix®) can be used ? 12 months as a last dose of the Hib schedule in children. Indications The Hib vaccine is a routine childhood vaccination (see Table: Recommended vaccination schedule for the age of 0-6 years). This vaccine is also recommended for adults with anatomic or functional asplenia, and those who are referred for elective splenectomy, if they are not immunized (ie, if they are not previously a primary series plus booster or ? 1 dose of Hib vaccine after the age of have received 14 months), although suggest some experts, given before elective splenectomy regardless of vaccination history a dose Immunocompromised adults (z. B. due to cancer chemotherapy or HIV infection), if they are not immunized individuals who have a transplantation of hematopoietic stem cells had, the most important contraindication is regardless of their vaccination history contraindications and precautions A severe allergic reaction (eg. , Anaphylaxis) after a previous dose or to a vaccine component The most important precaution is Moderate or severe illness with or without fever (vaccination, if possible, be postponed until the disease is over) Dosage and Administration The Hib vaccine is considered 0 , in 5 ml administered. A primary vaccination in childhood consists of 3 doses at the age of 2, 4, and 6 months or in 2 doses at age 2 and 4 months, depending on the substance. In any case, a booster at the age of 12 – 15 months recommended. One dose is given older children, adolescents and adults who have asplenia or who are referred for elective splenectomy, if they are not immunized. Some experts propose to administer a dose regardless of vaccination history before elective splenectomy. The dose is, if possible, given ? 14 days before elective splenectomy. A treatment regimen consisting of 3 doses, is administered 6 to 12 months after transplantation of hematopoietic stem cells; the cans are ? 4 weeks apart. Side effects are rare, you can also include fever, crying and irritability pain, redness and swelling at the injection site and in children.