Gilbert’S Syndrome

(Gilbert’s syndrome)

The Gilbert’s Syndrome is a life-long existing disorder in which the only visible symptom is a low unconjugated hyperbilirubinemia. Incorrectly, it can be regarded as chronic hepatitis or other liver disease.

The Gilbert’s Syndrome is a life-long existing disorder in which the only visible symptom is a low unconjugated hyperbilirubinemia. Incorrectly, it can be regarded as chronic hepatitis or other liver disease.

See also liver structure and function and evaluation of the patients with liver disease). The Gilbert’s Syndrome is a life-long existing disorder in which the only visible symptom is a low unconjugated hyperbilirubinemia. Incorrectly, it can be regarded as chronic hepatitis or other liver disease. The syndrome occurs in up to 5% of the population. Family members can be affected, a clear genetic pattern, however, is difficult to determine. The pathogenesis are complicated disorders Bilirubinaufnahme in the liver. The activity of the glucuronosyltransferase is reduced, but not as much as in Crigler-Najjar syndrome type II. In many patients, a slightly increased lysis of red blood cells is present, this increase does not explain the hyperbilirubinemia. Liver histology is normal. Gilbert’s syndrome is found mostly in young adults in the clarification of elevated bilirubin. This fluctuates usually between 2 to 5 mg / dl (34-86 .mu.mol / l) and increased by fasting or stress. The Gilbert’s Syndrome is the differential diagnosis of hepatitis delimited by an analysis of bilirubin, the v. a. unconjugated bilirubin shows. at Gilbert’s syndrome There are also normal liver function tests, urine there is no bilirubin. The demarcation hemolysis occurs by missing anemia and Reticulocytosis. Treatment is not necessary. Patients should be assured that they have no clinically liver Erkan Kung.

Health Life Media Team

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