Fibromuscular Dysplasia

The fibromuscular dysplasia is a heterogeneous group nichtarteriosklerotischer, nichtinflammatorischer arterial changes that cause a certain degree of stenosis, a shutter or an aneurysm.

The fibromuscular dysplasia usually occurs in women aged 40-60 years. The cause is unknown. However, there may be a genetic component and smoking may be a risk factor. The fibromuscular dysplasia is more common in people with certain connective tissue diseases (eg. As Ehlers-Danlos syndrome type 4, cystic medial, hereditary nephritis, neurofibromatosis).

The fibromuscular dysplasia is a heterogeneous group nichtarteriosklerotischer, nichtinflammatorischer arterial changes that cause a certain degree of stenosis, a shutter or an aneurysm. The fibromuscular dysplasia usually occurs in women aged 40-60 years. The cause is unknown. However, there may be a genetic component and smoking may be a risk factor. The fibromuscular dysplasia is more common in people with certain connective tissue diseases (eg. As Ehlers-Danlos syndrome type 4, cystic medial, hereditary nephritis, neurofibromatosis). The Mediadysplasie, the most common type, is determined by an alternation of regions with thick and thin fibromuscular rings which contain collagen along the median. The perimedialen dysplasia has a distinct collagen deposition in the outer half of the media. The fibromuscular dysplasia can affect the renal arteries (60-75%), the carotid arteries and intrakanielle (25-30%), intra-abdominal arteries (9%) or Aa. iliacae externae (5%). The fibromuscular dysplasia usually proceeds asymptomatically, independently of the location. Symptoms vary when they occur depending on the location: intermittent claudication, intermittent claudication, in the thighs and calves, a noise on the femoral arteries and an attenuated Femoralarterienpuls when leg arteries are affected Secondary hypertension if renal arteries are affected transient ischemic attack or stroke symptoms if carotid arteries are affected aneurysm symptoms when intracranial arteries are affected Rarely mesenteric ischemic symptoms when intra-abdominal arteries are affected an ultrasound can provide Hinwesie on the diagnosis; The definitive diagnosis is however provided by angiography showing a perlschnurartiges appearance (for medial or perimedialer dysplasia) or a concentric belt or long stretches of smooth narrowing (other forms). The treatment varies depending on the location. You may include a sole percutaneous transluminal angioplasty, percutaneous stent angioplasty, bypass surgery or aneurysm surgery. It is important to stop smoking. The control of other risk factors for atherosclerosis (hypertension, dyslipidemia, diabetes mellitus) helps prevent the accelerated development of flusslimitierenden arterial stenoses.

Health Life Media Team

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