Erythromelalgia

The erythromelalgia is a painful paroxysmal vasodilation of the small arteries of the feet and hands and less often on the face, ears or knees; it causes burning pain, increased skin temperature and redness.

This rare disease may be primary (unknown cause) or secondary to myeloproliferative diseases (e.g., as polycythemia vera, thrombocythemia), hypertension, venous insufficiency, diabetes mellitus, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), lichen sclerosus, gout , spinal cord disease or multiple sclerosis occur. Less common is the disease with the use of some drugs (eg., Nifedipine, bromocriptine) in context. A rare hereditary form of erythromelalgia starts at birth or during childhood.

The erythromelalgia is a painful paroxysmal vasodilation of the small arteries of the feet and hands and less often on the face, ears or knees; it causes burning pain, increased skin temperature and redness. This rare disease may be primary (unknown cause) or secondary to myeloproliferative diseases (e.g., as polycythemia vera, thrombocythemia), hypertension, venous insufficiency, diabetes mellitus, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), lichen sclerosus, gout , spinal cord disease or multiple sclerosis occur. Less common is the disease with the use of some drugs (eg., Nifedipine, bromocriptine) in context. A rare hereditary form of erythromelalgia starts at birth or during childhood. The burning pain, heat and redness of the hands or feet take a few minutes to hours. In most patients, the symptoms are triggered by heat (temperature 29-32 ° C) and can typically after immersion in ice water. Trophic changes do not occur. Symptoms may remain mild for years or be strong enough to cause total disability. A generalized Vasomotorendysfunktion often, Raynaud’s syndrome can occur. The diagnosis is made clinically. The investigation is carried out to the causes to detect. Since the erythromelalgia a myeloproliferative disease can precede several years, repeated blood counts may be indicated. The differential diagnoses include post-traumatic dystrophy, shoulder-hand syndrome, peripheral neuropathy, causalgia, Fabry’s disease and bacterial cellulitis. The treatment consists of heat avoidance, rest, elevation of extremities, and application of cold. For primary erythromelalgia gabapentin may be of use. In secondary erythromelalgia the underlying disease is treated; Acetylsalicylic acid can be helpful when a myeloproliferative disease is involved.

Health Life Media Team

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