For more information, s. DTaP ACIP (Advisory Committee on Immunization Practices) Vaccine Recommendations. Preparations diphtheria (D) – vaccines contain toxoids prepared from Corynebacterium diphtheriae. Tetanus (T) vaccines include toxoids prepared from Clostridium tetani. Acellular (a) pertussis (P) vaccines containing semi-purified or purified components of Bordetella pertussis. Whole-cell pertussis vaccine is no longer available in the United States because of concerns about side effects, but it is still available in other parts of the world. There are two acellular vaccine preparations: DTaP for children <7 years Tdap for adolescents and adults Tdap contains lower doses of diphtheria and pertussis components (indicated by the lower case d and p). Indications DTaP is a routine childhood vaccination (see Table: Recommended vaccination schedule for the age of 0-6 years). Tdap is routinely used as a single lifetime dose in children aged 11 or 12 years and persons ? 13 years Tdap have never received (regardless of the interval since the last tetanus-diphtheria [Td] vaccination tetanus diphtheria vaccine) or whose vaccination status is unknown administered. are additional boosts of Tdap also recommended for pregnant women during each pregnancy (preferably in the 27 to 36 weeks), regardless of the interval since a previous dose of Tdap women after childbirth, the Tdap have never received, and not during pregnancy were vaccinated adults require tetanus vaccine as part of a wound treatment contained a toxoid and the Tdap have not received previously, is Tdap instead of Td administered. Persons who have had pertussis should receive a pertussis-containing vaccine according to the routine recommendations, yet. Contraindications and precautions contraindications for DTaP and Tdap are a severe allergic reaction (e.g., anaphylaxis.) After the previous dose, or a vaccine component for the pertussis component: encephalopathy (. E.g., coma, decreased level of consciousness, prolonged seizures) located within occurred and 7 days of a previous dose of DTaP or Tdap can not be attributed to another identifiable cause Since the tetanus vaccination is important, persons who have had an anaphylactic reaction to components in DTaP or Tdap, be referred to an allergist to to determine whether they are allergic to tetanus toxoid. If not, they can be vaccinated with tetanus toxoid (TT) vaccine. Adults with a history of encephalopathy can be vaccinated with Td Tdap instead and children can Diphtheria-Tetanus (DT) are added. The precautions vary depending on the substance. For DTaP and Tdap they comprise Moderate or severe acute illness with or without fever (vaccination, if possible, be postponed until the disease is over) Guillain-Barre syndrome within 6 weeks after a previous dose of a vaccine, the tetanus toxoid containing only for the pertussis component: a progressive or unstable neurological disorder, uncontrolled seizures or progressive encephalopathy (vaccination will be postponed until a treatment regimen has been established and the disease stabilized) for DTaP precautions include a seizure (with or without fever) within 3 days after a previous dose of DTaP ? 3 hours lasting, heavy, inconsolable crying or wines within 48 hours after the previous dose of DTaP collapse or shock-like state (hypotonic hyporesponsiveness episode) in nerhalb of 48 hours after the previous dose of DTaP body temperature of ? 40.5 ° C, which can not be explained by any other cause, within 48 hours after the previous dose of DTaP only Tdap precautions include the history of the type III hypersensitivity reactions by prior administration of a vaccine, the tetanus or diphtheria toxoid containing (vaccination is ? 10 years since the last dose of tetanus toxoid-containing vaccine moved) dosage and administration the dose of DTaP or Tdap is 0.5 ml, The DTaP vaccine is as 5 primary immunization and booster 1 i.m. injected what happens during childhood as follows: at the age of 2 months, 4 months, 6 months, 15 to 18 months and 4 to 6 years (before starting school). The fifth dose is not necessary if the fourth dose was administered at age ? 4 years. A single booster of Tdap is administered, except pregnant women who should receive one dose during each pregnancy. Side effects are rare and the pertussis component are usually attributed. You can become noticeable as encephalopathy (within 7 days); Seizures, with or without fever (within 3 days); ? 3 hours persistent, severe Scream or wine spasms within 48 hours; Circulatory collapse and shock (within 48 hours); Temperature ? 40.5 ° C, which is not explained by other causes (within 48 h); as well as severe or anaphylactic reactions to the vaccine. If the pertussis vaccine is contraindicated, a combined diphtheria and tetanus vaccine is also available without the pertussis (tetanus-diphtheria vaccine). To the weak side effects include redness, swelling and pain at the injection site.