Definition: Leukopenia, Neutropenia And Monocytopenia

When neutropenia neutrophil count is reduced with pale skin to <1,500 / ul and dark-skinned to <1,200 / ul. It is more serious when it is accompanied by a Monocytopenia and lymphopenia. Lymphocytopenia, defined as absolute lymphocyte count <1000 / ul in adults is not always recognized as a decrease in the total number of white blood cells, since lymphocytes make up only 20-40% of the total number of white blood cells.

Leukopenia is a decrease in white blood cells to <4000 / ul. Usually it is characterized by a reduced number of circulating neutrophils but also reduced lymphocyte, monocyte, eosinophil or Basophilenzahlen can contribute to a reduction in cell number. As a result, the immune system is significantly weakened. When neutropenia neutrophil count is reduced with pale skin to <1,500 / ul and dark-skinned to <1,200 / ul. It is more serious when it is accompanied by a Monocytopenia and lymphopenia. Lymphocytopenia, defined as absolute lymphocyte count <1000 / ul in adults is not always recognized as a decrease in the total number of white blood cells, since lymphocytes make up only 20-40% of the total number of white blood cells. Monocytopenia was formerly not considered as a separate appearance; younger notes, however, have hinted that the lack or absence of monocytes in patients with mutations of the hematopoietic transcription factor gene, GATA2, may occur. Affected patients often present with a non-tuberculous mycobacterial infection, especially in cutaneous sites (i. E. MonoMac syndrome), or a genital HPV infection that has a high risk of progression to genital cancer,. There is a risk of progression to other hematological diseases before (eg., Bone marrow failure, acute myeloid leukemia, chronic myelomonocytic leukemia). The Monocytopenia is diagnosed through a blood count with differential blood count. The treatment is experimental and may interferon antibodies and allogeneic hematopoietic stem cell transplantation include, depending on the severity of the disorder and the development of secondary hematological diseases.

Health Life Media Team

Leave a Reply