Congenital Neurologic Abnormalities At A Glance

Some of the most severe neurological abnormalities (eg. As anencephaly [anencephaly], encephalocele [encephalocele], spina bifida [spina bifida]) develop in the first two months of pregnancy and make defects of Neuralrohrbildung represents (Dysrhaphie). Others, such as lissencephaly (malformations of the cerebral hemispheres: lissencephaly) are a result of a disturbance of neuronal migration (malformations of the cerebral hemispheres) 9 to 24 of gestation. Hydranencephaly (Porencephaly: Hydranencephaly) and Porencephaly (Porencephaly) are sequences of a secondary destruction after the brain has been formed. Some abnormalities (eg. As meningocele) are relatively benign.

Congenital abnormalities of the brain usually cause severe neurological deficits; some can be fatal. Some of the most severe neurological abnormalities (eg. As anencephaly [anencephaly], encephalocele [encephalocele], spina bifida [spina bifida]) develop in the first two months of pregnancy and make defects of Neuralrohrbildung represents (Dysrhaphie). Others, such as lissencephaly (malformations of the cerebral hemispheres: lissencephaly) are a result of a disturbance of neuronal migration (malformations of the cerebral hemispheres) 9 to 24 of gestation. Hydranencephaly (Porencephaly: Hydranencephaly) and Porencephaly (Porencephaly) are sequences of a secondary destruction after the brain has been formed. Some abnormalities (eg. As meningocele) are relatively benign. Many malformations can already in utero via amniocentesis (methods: amniocentesis) are detected and sonography (ultrasonography methods). The parents need if a malformation is discovered, psychological support and genetic counseling, as the risk for a subsequent child with such a deformity is very high. Preventing women who already have a fetus or a child with a neural tube defect, have a high risk and should be 4 mg (4000 micrograms) po once / day beginning 3 mo before conceptio) folate (folic acid folate) po as favorite supplements from 3 months to take once a day before conception and continue throughout the first trimester through. Additional folic acid doses help reduce the risk of neural tube defects in subsequent pregnancies by 75%. All women of childbearing age who had no fetus or infant with a neural tube defect should consume at least 400 micrograms / day of folic acid in the diet or as a substitution (some experts recommend 800 micrograms / day, to reduce further risk) and during continue the first trimester. Although this supplement folic acid reduces the risk of having a child with a neural tube defect, the degree of risk reduction is lower than in women who have already had a fetus or newborn baby with a neural tube defect (z. B. Risk reduction is <75%).

Health Life Media Team

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